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ABS433 Anti-IL-32 Antibody

Anti-IL-32 Antibody is a highly specific rabbit polyclonal antibody, that targets IL-32 & has been tested in western blotting, IHC & Immunofluorescence.

Anti-IL-32 Antibody: Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.
Research Category: Signaling Research Sub-Category: Developmental Signaling Gene Symbol: IL32 UniProt Number: P24001
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ABS433
100 µg  
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      Tabla espec. clave

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, IHC, IFRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABS433
      DescriptionAnti-IL-32 Antibody
      Alternate Names
      • Interleukin-32
      • IL-32
      • Natural killer cells protein 4
      • Tumor necrosis factor alpha-inducing factor
      • NK4
      • TAIF
      Background InformationInterleukin-32 (IL-32), also known as Natural killer cells protein 4 (NK4) and Tumor necrosis factor alpha-inducing factor (TAIF), may play a role in innate and adaptive immune responses. IL-32 induces various cytokines such as TNFA/TNF-alpha, MIP-2 and IL-8, and activates typical cytokine signal pathways of NF-kappa-B and p38 MAPK. IL-32 has been shown to be induced in human peripheral lymphocyte cells after mitogen stimulation and in epithelial cells by IFN gamma, and it has been suggested to play a role in autoimmune and inflammatory diseases such as rheumatoid arthritis. IL-32 is different from other known cytokine families because it does not share sequence homology with them and is highly expressed in immune tissues, existing in at least four differentially spliced isoforms. IL-32 is selectively expressed in lymphocytes and expression is more prominent in immune cells than in non-immune cells. The expression of IL-32 increased after activation of T-cells by mitogens and after activation of NK cells by IL2/interleukin-2.
      References
      Product Information
      FormatAffinity Purified
      Control
      • Human spleen tissue lysate
      PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-IL-32 Antibody is a highly specific rabbit polyclonal antibody, that targets IL-32 & has been tested in western blotting, IHC & Immunofluorescence.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      • Immunofluorescence
      Application NotesImmunohistochemistry Analysis: 10 µg/mL from a representative lot detected IL-32 in human spleen tissue.

      Immunofluorescence Analysis: 20 µg/mL from a representative lot detected IL-32 in human spleen cells.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to the C-terminus of human IL-32.
      EpitopeC-terminus
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityThis antibody recognizes two isoforms at ~14 kDa and ~22 kDa at the C-terminus of IL-32.
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • IL32
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~14 kDa and ~22 kDa observed. Uncharacterized bands may appear in some lysate(s). Uniprot describes 5 isoforms between ~15 kDa and ~27 kDa.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in human spleen tissue lysate.

      Western Blot Analysis: 5 µg/mL of this antibody detected IL-32 in 15 µg of human spleen tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      ABS433 04053252910166