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ABE492 Anti-Histone lysine demethylase NO66 Antibody

Detect NO66 using this rabbit polyclonal antibody, Anti-Histone lysine demethylase NO66 Antibody validated for use in western blotting.

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Research Category: Epigenetics & Nuclear Function Research Sub-Category: Chromatin Biology Gene Symbol: NO66, C14orf169, MAPJD UniProt Number: Q9H6W3
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ABE492
100 µg  
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      Tabla espec. clave

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWBRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABE492
      DescriptionAnti-Histone lysine demethylase NO66 Antibody
      Alternate Names
      • Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66
      • 60S ribosomal protein L8 histidine hydroxylase
      • Histone lysine demethylase NO66
      • Myc-associated protein with JmjC domain
      • Nucleolar protein 66
      • hsNO66
      • Ribosomal oxygenase NO66
      • ROX
      • NO66
      Background InformationNO66 is a lysine-specific demethylase that removes methyl groups from histone H3 at lysine 4 and lysine 36. This enzyme has been shown to more readily demethylate trimethylated H3 'Lys-4' (H3K4me3) and monomethylated H3 Lys4 (H3K4me1) consistent with its role in modulating the histone code. This protein is a highly conserved, constitutive nucleolar component that shows a dual localization pattern with strong enrichment in the granular part of nucleoli and in distinct nucleoplasmic entities.
      References
      Product Information
      FormatAffinity Purified
      Control
      • A431 cell lysate
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationDetect NO66 using this rabbit polyclonal antibody, Anti-Histone lysine demethylase NO66 Antibody validated for use in western blotting.
      Key Applications
      • Western Blotting
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human Histone lysine demethylase NO66 near the N-terminus.
      EpitopeNear N-terminus
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityThis antibody recognizes Histone lysine demethylase NO66 near the N-terminus.
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • NO66
      • C14orf169
      • MAPJD
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~66 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in A431 cell lysate.

      Western Blotting Analysis: 2.0 µg/mL of this antibody detected Histone lysine demethylase NO66 in 10 µg of A431 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      ABE492 04053252910814