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MABN356 Anti-FKBP4 Antibody, clone 2H9.1

Anti-FKBP4 Antibody, clone 2H9.1 is an antibody against FKBP4 for use in western blotting & IHC (Paraffin).

Anti-FKBP4 Antibody, clone 2H9.1: Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.
Research Category: Neuroscience Research Sub-Category: Developmental Signaling Gene Symbol: FKBP4, FKBP52 UniProt Number: Q02790
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MABN356
100 µg  
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      Tabla espec. clave

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, IH(P)MPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABN356
      DescriptionAnti-FKBP4 Antibody, clone 2H9.1
      Alternate Names
      • Peptidyl-prolyl cis-trans isomerase FKBP4
      • PPIase FKBP4
      • 51 kDa FK506-binding protein
      • FKBP51
      • 52 kDa FK506-binding protein
      • 52 kDa FKBP
      • FKBP-52
      • 59 kDa immunophilin
      • p59
      • FK506-binding protein 4
      • FKBP-4
      • FKBP59
      • HSP-binding immunophilin
      • HBI
      • Immunophilin FKBP52
      • Rotamase
      • Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed
      Background InformationFKBP4, also known as Peptidyl-prolyl cis-trans isomerase FKBP4 (PPIase FKBP4), or 51 kDa FK506-binding protein (FKBP51), 52 kDa FK506-binding protein (FKBP-52), or 59 kDa immunophilin (p59), or FK506-binding protein 4 (FKBP-4) or FKBP59 , or HSP-binding immunophilin (HBI), or Immunophilin FKBP52 Rotamase, and encoded by the gene FKBP4/FKBP62 is a chaperon type protein that is involved in protein folding and trafficking and the immunoregulation of cellular responses. FKBP4 is a member of the immunophilin family of proteins. FKBP4 forms a component of unligated steroid receptors complexes and helps in the cycling of the receptors between the cytoplasm and nuclear compartments. FKBP4 also plays a role in regulating neuronal growth cones via the regulations of TRPC1 channels, and FKBP4 modules microtubule dynamics by inhibiting MAPT/TAU in microtubule assembly. Finally, FKBP4 also influences the regulation and modulation oxidative stress in mitochondria. FKBP4 will localize to the cytoplasm, mitochondria or nucleus depending upon cellular situation and is widely expressed.
      References
      Product Information
      FormatPurified
      PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-FKBP4 Antibody, clone 2H9.1 is an antibody against FKBP4 for use in western blotting & IHC (Paraffin).
      Key Applications
      • Western Blotting
      • Immunohistochemistry (Paraffin)
      Application NotesImmunohistochemistry Analysis: A 1:500 dilution from a representative lot detected FKBP4 in human testis and human cerebellum tissue.
      Biological Information
      ImmunogenGST-tagged recombinant protein corresponding to the C-terminus of human FKBP4.
      EpitopeC-terminus
      Clone2H9.1
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      IsotypeIgG1κ
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • FKBP4
      • FKBP52
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~52 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in T47D cell lysate.

      Western Blotting Analysis: 0.25 µg/mL of this antibody detected FKBP4 in 10 µg of T47D cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      MABN356 04053252942778