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MAB430-I-25UG Anti-Epithelium Endothelial Cells Antibody, clone PHM-5

Anti-Epithelium Endothelial Cells, clone PHM-5, Cat. No. MAB430-I, is a mouse monoclonal antibody that detects human human epithelium/endothelial cells and has been tested for use in Immunohistochemistry (Paraffin).

Research Category: Cell Structure
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MAB430-I-25UG
25 μg  
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      Descripción

      Replacement Information

      Tabla espec. clave

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HIH(P)MPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMAB430-I-25UG
      DescriptionAnti-Epithelium Endothelial Cells Antibody, clone PHM-5
      Alternate Names
      • Glomerular endothelial cells
      • Glomerular epithelial cells
      Background InformationThe glomeruli network of capillaries filters the blood and the filtrate then enters the renal tubule. Unlike most capillary beds, the glomerular capillaries exit into efferent arterioles rather than venules. The resistance that exists in efferent arterioles causes sufficient hydrostatic pressure within the glomerulus to provide the force for ultrafiltration. Glomerular endothelial cells that create an interface between blood and tissue compartments are responsible for regulating vasomotor tone, trafficking of leukocytes, and maintenance of maintain hemostasis. Unlike endothelium in other tissues, the normal glomerular endothelium is extremely attenuated, being only about 50 to 150 nm in height around the perimeter of the capillary loops. Glomeruli of human kidneys are shown to be rich sialoglycoprotein, which is chemically distinct from rat podocalyxin. (Ref.: Ballermann, BJ (2005). Kidney Int. 67(5); 1668-1671; Kerjaschki, D., et al. (1986). J. Clin. Invest. 78(5); 1142-1149).
      References
      Product Information
      FormatPurified
      PresentationPurified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Applications
      ApplicationAnti-Epithelium Endothelial Cells, clone PHM-5, Cat. No. MAB430-I, is a mouse monoclonal antibody that detects human human epithelium/endothelial cells and has been tested for use in Immunohistochemistry (Paraffin).
      Key Applications
      • Immunohistochemistry (Paraffin)
      Application NotesImmunohistochemistry (Paraffin) Analysis: A 1:50 dilution from a representative lot detected Epithelium Endothelial Cells in human cerebral cortex tissue sections.
      Biological Information
      ImmunogenHuman Glomerular cells.
      Clone18.29 (PHM-5)
      ConcentrationPlease refer to lot specific datasheet.
      HostMouse
      SpecificityClone PHM-5 is a mouse monoclonal antibody that detects human epithelium/endothelial cells.
      IsotypeIgG1κ
      Species Reactivity
      • Human
      Species Reactivity NoteHuman.
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Purification MethodProtein G purified
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Immunohistochemistry (Paraffin) in human kidney tissue sections.

      Immunohistochemistry (Paraffin) Analysis: A 1:50 dilution of this antibody detected Epithelium Endothelial Cells in human kidney tissue sections.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size25 μg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      MAB430-I-25UG 04054839510113

      Documentation