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CBL251 Anti-Epithelial Specific Antigen Antibody, clone VU-1D9

Anti-Epithelial Specific Antigen Antibody, clone VU-1D9 is a highly specific mouse monoclonal antibody, that targets Epithelial Cell Marker & has been tested in western blotting, ICC & IHC.

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Research Category: Cell Structure Research Sub-Category: ECM Proteins Gene Symbol: EPCAM, GA733-2, M1S2, M4S1, MIC18, TACSTD1, TROP1 UniProt Number: P16422
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CBL251
100 µg  
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      Tabla espec. clave

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, ICC, IHCMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberCBL251
      DescriptionAnti-Epithelial Specific Antigen Antibody, clone VU-1D9
      Alternate Names
      • Epithelial cell adhesion molecule
      • Ep-CAM
      • Adenocarcinoma-associated antigen
      • Cell surface glycoprotein Trop-1
      • Epithelial cell surface antigen
      • Epithelial glycoprotein
      • EGP
      • Epithelial glycoprotein 314
      • EGP314
      • hEGP314
      • KS 1/4 antigen
      • KSA
      • Major gastrointestinal tumor-associated protein GA733-2
      • Tumor-associated calcium signal transducer 1
      • CD326
      Background InformationEpithelial specific antigen, also known as epithelial cell adhesion molecule (Ep-CAM) and epithelial glycoprotein (EGP), may act as an interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Epithelial specific antigen plays a role in embryonic stem cells proliferation and differentiation, and up-regulates the expression of FABP5, MYC, and cyclins A and E. Epithelial specific antigen is highly and selectively expressed by undifferentiated embryonic stem cells (ESCs). Protein levels rapidly diminish as soon as ESCs differentiate. Also expressed in most epithelial cell membranes and on the surface of adenocarcinoma.
      Product Information
      FormatPurified
      Control
      • MCF7 cell lyasate
      PresentationPurified mouse monoclonal IgG1κ in buffer containing PBS with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-Epithelial Specific Antigen Antibody, clone VU-1D9 is a highly specific mouse monoclonal antibody, that targets Epithelial Cell Marker & has been tested in western blotting, ICC & IHC.
      Key Applications
      • Western Blotting
      • Immunocytochemistry
      • Immunohistochemistry
      Application NotesImmunocytochemistry Analysis: A 1:500 dilution from a representative lot detected Epithelial Specific Antigen in A431 cells.

      Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Epithelial Specific Antigen in human prostate adenocarcinoma cells.
      Biological Information
      ImmunogenNCI-H69 whole cells
      CloneVU-1D9
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      IsotypeIgG1κ
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • EPCAM
      • GA733-2
      • M1S2
      • M4S1
      • MIC18
      • TACSTD1
      • TROP1
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~40 kDa observed. The calculated molecular weight of this protein is 35 kDa; however, this protein will run higher due to glycosylation.
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in MCF7 cell lyate.

      Western Blotting Analysis: 1 µg/mL of this antibody detected Epithelial Specific Antigen in 10 µg of MCF7 cell lyate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Global Trade Item Number
      Número de referencia GTIN
      CBL251 04053252280955