Millipore Sigma Vibrant Logo

MAB3775 Anti-Cdc20 Antibody, clone AR12

Anti-Cdc20 Antibody, clone AR12 is a Mouse Monoclonal Antibody for detection of Cdc20 also known as Cell Division Cycle Protein 20 Homolog p55cdc & has been validated in IF & IP.

Anti-Cdc20 Antibody, clone AR12: Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.
Research Category: Epigenetics & Nuclear Function Research Sub-Category: Cell Cycle, DNA Replication & Repair Gene Symbol: CDC20, CDC20A, MGC102824, p55CDC, P55CDC-LSB, bA276H19.3 UniProt Number: Q12834
View Products on Sigmaaldrich.com
MAB3775
100 µg  
Recuperando precio...
No pudo obtenerse el precio
La cantidad mínima tiene que ser múltiplo de
Maximum Quantity is
Al finalizar el pedido Más información
Ahorró ()
 
—
Solicitar precio
—
Disponibilidad a confirmar Disponibilidad a confirmar
Ingrese cantidad 
Suspendido
Cantidades limitadas disponibles
Debe confirmarse disponibilidad
    El resto: se avisará
      El resto: se avisará
      Se avisará
      Póngase en contacto con el Servicio de Atención al Cliente
      Contact Customer Service

      Ofertas especiales

       

      Póngase en contacto con el Servicio de Atención al Cliente

      Descripción

      Replacement Information

      Ofertas especiales

      100% Performance Guaranteed

      Tabla espec. clave

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HIF, IPMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMAB3775
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Cdc20 Antibody, clone AR12
      Alternate Names
      • Cell Division Cycle Protein 20 Homolog
      • p55cdc
      References
      Product Information
      FormatPurified
      PresentationPurified immunoglobulin. Liquid in 0.02M phosphate buffer, 0.25M NaCl, pH 7.6, with 0.1% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-Cdc20 Antibody, clone AR12 is a Mouse Monoclonal Antibody for detection of Cdc20 also known as Cell Division Cycle Protein 20 Homolog p55cdc & has been validated in IF & IP.
      Key Applications
      • Immunofluorescence
      • Immunoprecipitation
      Application NotesImmunofluorescence

      Immunoprecipitation

      Optimal working dilutions must be determined by end user.
      Biological Information
      ImmunogenHuman Cdc20 recombinant protein
      CloneAR12
      HostMouse
      SpecificityRecognizes human Cdc20
      IsotypeIgG1
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryCDC20 appears to act as a regulatory protein interacting with several other proteins at multiple points in the cell cycle. It is required for two microtubule-dependent processes, nuclear movement prior to anaphase and chromosome separation.
      Gene Symbol
      • CDC20
      • CDC20A
      • MGC102824
      • p55CDC
      • P55CDC-LSB
      • bA276H19.3
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: Q12834 # Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1. In metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates.
      SIZE: 499 amino acids; 54723 Da
      SUBUNIT: Found in a complex with CDC20, CDC27, SPATC1 and TUBG1. Interacts with SPATC1 (By similarity). Interacts with MAD2L1. The phosphorylated form interacts with APC/C.
      DEVELOPMENTAL STAGE: Synthesis is initiated at G1/S, protein level peaks in M phase and protein is abruptly degraded at M/G1 transition.
      PTM: Phosphorylated during mitosis, probably by maturation promoting factor (MPF).
      SIMILARITY: SwissProt: Q12834 ## Belongs to the WD repeat CDC20/Fizzy family. & Contains 7 WD repeats.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at 2-8°C in undiluted aliquots for up to 12 months from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      MAB3775 04053252610776

      Documentation

      Anti-Cdc20 Antibody, clone AR12 Ficha datos de seguridad (MSDS)

      Título

      Ficha técnica de seguridad del material (MSDS) 

      Anti-Cdc20 Antibody, clone AR12 Certificados de análisis

      CargoNúmero de lote
      MOUSE ANTI-HUMAN CDC20 MONOCLONAL ANTIBODY - 2429677 2429677
      MOUSE ANTI-HUMAN CDC20 MONOCLONAL ANTIBODY - 2446942 2446942
      MOUSE ANTI-HUMAN CDC20 - 3387603 3387603
      MOUSE ANTI-HUMAN CDC20 - 3537614 3537614
      MOUSE ANTI-HUMAN CDC20 - 4164551 4164551
      MOUSE ANTI-HUMAN CDC20 -2694561 2694561
      MOUSE ANTI-HUMAN CDC20 -2725234 2725234
      MOUSE ANTI-HUMAN CDC20 -2817702 2817702
      MOUSE ANTI-HUMAN CDC20 MONOCLONAL ANTIBODY 3084147
      MOUSE ANTI-HUMAN CDC20 MONOCLONAL ANTIBODY 2926496
      Show more

      Referencias bibliográficas

      Visión general referenciasPub Med ID
      Mad2 binding to Mad1 and Cdc20, rather than oligomerization, is required for the spindle checkpoint.
      Sironi, L, et al.
      EMBO J., 20: 6371-82 (2001)  2001

      Mostrar resumen       		11707408 11707408