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119135 Adenosine A1 Receptor Agonist I, CPA - CAS 41552-82-3 - Calbiochem

Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.

Sinónimos: (2R,3R,4S,5R)-2-(6-(cyclopentylamino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol, N6-Cyclopentyl-adenosine

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119135
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Replacement Information

Precios y disponibilidad

Número de referencia DisponiblidadEmbalaje Cant./Env. Precio Cantidad
119135-25MG
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      Description
      OverviewA potent and selective agonist of adenosine A1 receptor (A1R) (Ki = 2.3 nM, 790 nM, 18.6 µM, 43nM for human A1, A2A, A2B, and A3, respectively).
      Catalogue Number119135
      Brand Family Calbiochem®
      Synonyms(2R,3R,4S,5R)-2-(6-(cyclopentylamino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol, N6-Cyclopentyl-adenosine
      References
      ReferencesMigita, H., et al. 2008. J Neurosci Res. 86, 2820.
      Burgdorf, C. et al. 2005. J Cardiovasc Pharmacol. 45, 1.
      Klotz, K. N., et al. 2000. Naunyn Schmiedebergs Arch Pharmacol. 362, 382.
      Mironov, S., et al. 1990. J Neurophysiol. 81, 1.
      Monopoli, A., et al. 1994. Arzneimittelforschung. 44, 1305.
      Concas, A., et al. 1993. J Pharmacol Exp Ther. 267, 844.
      Lohse, M. J., et al. 1988. Nauryn Schmiedebergs Arch Pharmacol. 337, 687.
      Coffin, V. L., et al. 1987. J Pharmacol Exp Ther. 241, 76.
      Product Information
      CAS number41552-82-3
      FormWhite solid
      Hill FormulaC₁₅H₂₁N₅O₄
      Chemical formulaC₁₅H₂₁N₅O₄
      ReversibleY
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetA1
      Primary Target K<sub>i</sub>0.8 nM
      Purity≥99% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      119135-25MG 04055977223316

      Documentation

      Adenosine A1 Receptor Agonist I, CPA - CAS 41552-82-3 - Calbiochem Ficha datos de seguridad (MSDS)

      Título

      Ficha técnica de seguridad del material (MSDS) 

      Adenosine A1 Receptor Agonist I, CPA - CAS 41552-82-3 - Calbiochem Certificados de análisis

      CargoNúmero de lote
      119135

      Referencias bibliográficas

      Visión general referencias
      Migita, H., et al. 2008. J Neurosci Res. 86, 2820.
      Burgdorf, C. et al. 2005. J Cardiovasc Pharmacol. 45, 1.
      Klotz, K. N., et al. 2000. Naunyn Schmiedebergs Arch Pharmacol. 362, 382.
      Mironov, S., et al. 1990. J Neurophysiol. 81, 1.
      Monopoli, A., et al. 1994. Arzneimittelforschung. 44, 1305.
      Concas, A., et al. 1993. J Pharmacol Exp Ther. 267, 844.
      Lohse, M. J., et al. 1988. Nauryn Schmiedebergs Arch Pharmacol. 337, 687.
      Coffin, V. L., et al. 1987. J Pharmacol Exp Ther. 241, 76.
      Ficha técnica

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision28-March-2013 JSW
      Synonyms(2R,3R,4S,5R)-2-(6-(cyclopentylamino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol, N6-Cyclopentyl-adenosine
      DescriptionA potent and selective agonist of adenosine A1 receptor (A1R) (Ki = 2.3 nM, 790 nM, 18.6 µM, 43nM for human A1, A2A, A2B, and A3, respectively).
      FormWhite solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number41552-82-3
      Chemical formulaC₁₅H₂₁N₅O₄
      Structure formulaStructure formula
      Purity≥99% by HPLC
      SolubilityDMSO (100 mM), 1N HCl (100 mM), or Ethanol (25 mM; slight warming is required for complete solubilization in ethanol)
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesMigita, H., et al. 2008. J Neurosci Res. 86, 2820.
      Burgdorf, C. et al. 2005. J Cardiovasc Pharmacol. 45, 1.
      Klotz, K. N., et al. 2000. Naunyn Schmiedebergs Arch Pharmacol. 362, 382.
      Mironov, S., et al. 1990. J Neurophysiol. 81, 1.
      Monopoli, A., et al. 1994. Arzneimittelforschung. 44, 1305.
      Concas, A., et al. 1993. J Pharmacol Exp Ther. 267, 844.
      Lohse, M. J., et al. 1988. Nauryn Schmiedebergs Arch Pharmacol. 337, 687.
      Coffin, V. L., et al. 1987. J Pharmacol Exp Ther. 241, 76.