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662006 U0124 - CAS 1140528-25-1 - Calbiochem

A useful negative control for MEK inhibitors U0125 and U0126.

U0124 - CAS 1140528-25-1 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 1,4-Diamino-2,3-dicyano-1,4-bis(methylthio)butadiene

Primary Target: MEK1
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662006
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
1140528-25-1C₈H₁₀N₄S₂

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      Description
      OverviewA useful negative control for MEK inhibitors U0125 (Cat. No. 662008) and U0126 (Cat. No. 662005). Does not inhibit MEK activity even at concentrations of 100 µM.
      Catalogue Number662006
      Brand Family Calbiochem®
      Synonyms1,4-Diamino-2,3-dicyano-1,4-bis(methylthio)butadiene
      References
      ReferencesFavata, M.F., et al. 1998. J. Biol. Chem. 273, 18623.
      Product Information
      CAS number1140528-25-1
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₈H₁₀N₄S₂
      Chemical formulaC₈H₁₀N₄S₂
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetMEK1
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 weeks at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      662006-1MG 04055977261028

      Documentation

      U0124 - CAS 1140528-25-1 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      U0124 - CAS 1140528-25-1 - Calbiochem Certificates of Analysis

      TitleLot Number
      662006

      References

      Reference overview
      Favata, M.F., et al. 1998. J. Biol. Chem. 273, 18623.

      Citations

      Title
    • Neelakandan Muthukumaran, et al. (2006) Tumor necrosis factor-α differentially modulates CD44 expression in ovarian cancer cells. Molecular Cancer Research 4, 511-520.
      		•
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision19-April-2011 RFH
      Synonyms1,4-Diamino-2,3-dicyano-1,4-bis(methylthio)butadiene
      DescriptionA useful negative control for the MEK inhibitors U0125 (Cat. No. 662008) and U0126 (Cat. No. 662005). Does not inhibit MEK even at concentrations of 100 µM.
      FormWhite solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number1140528-25-1
      Chemical formulaC₈H₁₀N₄S₂
      Structure formulaStructure formula
      Purity≥95% by HPLC
      SolubilityDMSO (100 mg/ml)
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 weeks at -20°C.
      Toxicity Standard Handling
      ReferencesFavata, M.F., et al. 1998. J. Biol. Chem. 273, 18623.
      Citation
    • Neelakandan Muthukumaran, et al. (2006) Tumor necrosis factor-α differentially modulates CD44 expression in ovarian cancer cells. Molecular Cancer Research 4, 511-520.
      		•