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582235 Tetanus Toxin, C-Fragment, Clostridium tetani - Calbiochem

The C-terminal binding portion of the heavy chain of tetanus toxin.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: TsTx-KαTTC

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      Overview

      Replacement Information
      Description
      OverviewThe C-terminal binding portion of the heavy chain of tetanus toxin. Useful for binding studies.
      Caution: may contain trace amounts of intact toxin.
      Catalogue Number582235
      Brand Family Calbiochem®
      SynonymsTsTx-KαTTC
      References
      ReferencesPoulain, B. 1994. Pathol. Biol. 42, 173.
      Williamson, L.C., et. al. 1993. Soc. Neurosci. 19, Abstract 770.10.
      Evinger, C. and Erichsen, J.T. 1986. Brain Res. 380, 383.
      Helting, T.B. and Zwisler, O. 1977. J. Biol. Chem. 252, 187.
      Matsuda, M. and Yoneda, M. 1977. Biochem. Biophys. Res. Commun. 77, 268.
      Product Information
      ATP CompetitiveN
      FormLyophilized
      FormulationLyophilized from 10 mM sodium phosphate buffer, pH 7.5.
      ReversibleN
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetUseful for binding studies
      PuritySingle major band by SDS-PAGE
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 26/27/28

      Very toxic by inhalation, in contact with skin and if swallowed.
      S PhraseS: 45

      In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Highly Toxic
      Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
      Storage +2°C to +8°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage. Once an aliquot has been thawed, do not refreeze. Aqueous stock solutions are stable for 7-10 days at 4°C.
      Canadian export regulations Due to the country and/or U.S. state of origin of the animal material used in this product, this product may not be exported to Canada.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      582235 0

      Documentation

      Tetanus Toxin, C-Fragment, Clostridium tetani - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Tetanus Toxin, C-Fragment, Clostridium tetani - Calbiochem Certificates of Analysis

      TitleLot Number
      582235

      References

      Reference overview
      Poulain, B. 1994. Pathol. Biol. 42, 173.
      Williamson, L.C., et. al. 1993. Soc. Neurosci. 19, Abstract 770.10.
      Evinger, C. and Erichsen, J.T. 1986. Brain Res. 380, 383.
      Helting, T.B. and Zwisler, O. 1977. J. Biol. Chem. 252, 187.
      Matsuda, M. and Yoneda, M. 1977. Biochem. Biophys. Res. Commun. 77, 268.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision18-September-2007 RFH
      SynonymsTsTx-KαTTC
      DescriptionThe C-terminal binding portion of the chain of tetanus toxin. The intact toxin is known to block neurotransmitter release at inhibitory synapses in cultured spinal cord cells. Shows trans-synaptic retrograde transport in the central nervous system. Caution: may contain trace amounts of intact toxin. Follow the handling procedure described in the information that accompanies the product.
      FormLyophilized
      FormulationLyophilized from 10 mM sodium phosphate buffer, pH 7.5.
      PuritySingle major band by SDS-PAGE
      SolubilitySterile distilled H₂O
      Storage +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage. Once an aliquot has been thawed, do not refreeze. Aqueous stock solutions are stable for 7-10 days at 4°C.
      Toxicity Highly Toxic
      ReferencesPoulain, B. 1994. Pathol. Biol. 42, 173.
      Williamson, L.C., et. al. 1993. Soc. Neurosci. 19, Abstract 770.10.
      Evinger, C. and Erichsen, J.T. 1986. Brain Res. 380, 383.
      Helting, T.B. and Zwisler, O. 1977. J. Biol. Chem. 252, 187.
      Matsuda, M. and Yoneda, M. 1977. Biochem. Biophys. Res. Commun. 77, 268.