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GF176 TGF-β-III Protein, Human Recombinant

TGF-β-III (transforming growth factor beta III) is one of three closely related mammalian members of the large TGF-β superfamily.

TGF-β-III Protein, Human Recombinant MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
UniProt Number: P10600 Entrez Gene Number: 7043
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GF176
10µg  
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      Overview

      Replacement Information

      Key Spec Table

      SourcePurity
      E. coli.Product is endotoxin free (<0.1 ng/μg of protein (<1 EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses.
      Description
      Catalogue NumberGF176
      DescriptionTGF-β-III Protein, Human Recombinant
      Alternate Names
      • Transforming Growth Factor Beta 3
      • TGF-Beta-3
      • TGF-Beta-III
      Background InformationTGF-β-III (transforming growth factor beta III) is one of three closely related mammalian members of the large TGF-β superfamily. TGF-β-I, TGF-β-II and TGF-β-III are highly pleiotropic cytokines that are proposed to act as cellular switches that regulate processes such as immune function, proliferation and epithelial mesenchymal transition. TGF-β3 regulates molecules involved in cellular adhesion and extracellular matrix formation during the process of palate development. TGF-β3 also plays an essential role in controlling the development of lungs in mammals and controls wound healing by regulating the movements of epidermal and dermal cells in injured skin. Recombinant TGF-β-III is a 25.0 kDa protein composed of two identical 112 amino acid polypeptide chains linked by a single disulfide bond.
      References
      Product Information
      HS Code3002 15 90
      PresentationProduct is filtered through a 0.2 micron filter before lyophilization.
      Quality LevelMQ100
      Applications
      ApplicationTGF-β-III (transforming growth factor beta III) is one of three closely related mammalian members of the large TGF-β superfamily.
      Biological Information
      PurityProduct is endotoxin free (<0.1 ng/μg of protein (<1 EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses.
      SourceE. coli.
      Entrez Gene Number
      UniProt Number
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceDetermined by TGF-β-III’s ability to inhibit the mouse IL-4-dependent proliferation of mouse HT-2 cells. The expected ED50 is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 107 units/mg.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStore at -20°C for up to 6 months from date of receipt.
      Packaging Information
      Material Size10µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      GF176 04053252599675

      Documentation

      TGF-β-III Protein, Human Recombinant SDS

      Title

      Safety Data Sheet (SDS) 

      TGF-β-III Protein, Human Recombinant Certificates of Analysis

      TitleLot Number
      Recombinant Human TGF-#946;-III - Q2048992 Q2048992
      Recombinant Human -2579928 2579928
      Recombinant Human -2729464 2729464
      Recombinant Human -2732282 2732282
      Recombinant Human TGF--III - 2298445 2298445
      Recombinant Human TGF-β-III - 3326100 3326100
      Recombinant Human TGF-β-III - 3403265 3403265
      Recombinant Human TGF-β-III - 3504398 3504398
      Recombinant Human TGF-β-III - 3530663 3530663
      Recombinant Human TGF-β-III - 3587170 3587170
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      Related Products & Applications

      Product Families

      Cytokines and Growth Factors

      EMD Millipore offers a comprehensive range of highly purified bioactive cytokines and growth factors for use in human, mouse, and rat cell culture, stem cell differentiation and ELISA studies.
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      Categories

      Life Science Research > Proteins and Enzymes > Cytokines & Growth Factors
      Life Science Research > Cell Culture and Systems > Cell Culture Media and Supplements > Cell Culture Supplements > Cytokines & Growth Factors