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567430 Sodium Butyrate - CAS 156-54-7 - Calbiochem

Sodium Butyrate, CAS 156-54-7, is a short chain fatty acid that induces apoptosis in colon carcinoma cells by a p53-independent pathway. Down-regulates the activity of casein kinase II in HT29 cells.

Sodium Butyrate - CAS 156-54-7 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Butyric Acid, Na, NaB, HDAC Inhibitor V

Primary Target: Induce apoptosis
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567430
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Overview

Key Spec Table

CAS #Empirical Formula
156-54-7C₄H₇O₂Na

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567430-250MG
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      Description
      OverviewA short chain fatty acid that has been shown to induce apoptosis in colon carcinoma cell lines by a p53-independent pathway. Inhibits c-myc splicing and interferes with signal transduction processes, including the release of Ca2+ from intracellular stores. Reduces histamine-induced calcium mobilization in C6 glioma cells. Down-regulates the activity of the serine/threonine protein kinase casein kinase II in HT29 cells.
      Catalogue Number567430
      Brand Family Calbiochem®
      SynonymsButyric Acid, Na, NaB, HDAC Inhibitor V
      References
      ReferencesOu, H.C., et al. 1997. Neuroreport 8, 1375.
      Russo, G.L., et al. 1997. Biochem. Biophys. Res. Commun. 233, 673.
      Krupitza, G., et al. 1995. Carcinogenesis 16, 1199.
      Calabresse, C., et al. 1993. Biochem. Biophys. Res. Commun. 195, 31.
      Hague, A., et al. 1993. Int. J. Cancer 55, 498.
      Product Information
      CAS number156-54-7
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₄H₇O₂Na
      Chemical formulaC₄H₇O₂Na
      Hygroscopic Hygroscopic
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ200
      Applications
      ApplicationSodium Butyrate, CAS 156-54-7, is a short chain fatty acid that induces apoptosis in colon carcinoma cells by a p53-independent pathway. Down-regulates the activity of casein kinase II in HT29 cells.
      Biological Information
      Primary TargetInduce apoptosis
      Purity≥98% by titration
      Physicochemical Information
      Cell permeableN
      Safety Information according to GHS
      RTECSET6400000
      Safety Information
      R PhraseR: 20/21/22-36/37/38

      Harmful by inhalation, in contact with skin and if swallowed.
      Irritating to eyes, respiratory system and skin.
      S PhraseS: 26-36

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing.
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Irritant
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Global Trade Item Number
      Catalogue Number GTIN
      567430-250MG 04055977267273