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567333 SNAPtide® Botulinum Toxin A Substrate, Fluorogenic - Calbiochem

SNAPtide® Botulinum Toxin A Substrate, Fluorogenic, is a synthetic peptide that acts as a FRET substrate with the fluorophore o-aminobenzoic acid and the acceptor chromophore 2,4-dinitrophenol (DNP).

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567333
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Overview

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Catalogue Number AvailabilityPackaging Qty/Pack Price Quantity
567333-200NMOL
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      		 Plastic ampoule 200 nmol
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      Description
      OverviewA synthetic peptide, fluorescence resonance energy transfer (FRET) substrate containing the N-terminally-linked fluorophore o-aminobenzoic acid (Abz) and the acceptor chromophore 2,4-dinitrophenol (DNP) linked to the C-terminus. The substrate is based on the native botulinum toxin type A cleavage site found in the synaptosome-associated protein SNAP-25. Cleavage of the substrate by botulinum toxin releases the fluorophore and full fluorescence is restored.
      Catalogue Number567333
      Brand Family Calbiochem®
      References
      ReferencesBigalke, H. and Shoer, L.F. 2000. In: Handbook of Experimental Pharmacology, 145, Bacterial Protein Toxins (K. Aktories and I. Just, Eds.) pp. 407-443, Springer-Verlag, Berlin.
      Schiavo, G., et al. 1993. J. Biol. Chem. 268, 23784.
      Product Information
      ATP CompetitiveN
      FormLyophilized
      FormulationLyophilized from water.
      ReversibleN
      Quality LevelMQ100
      Biological Information
      Primary TargetSubstrate for the native botulinum toxin
      Purity≥90% by HPLC
      Physicochemical Information
      Cell permeableN
      Emission max.
      Excitation max.
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot, cover with foil to protect from light, and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Global Trade Item Number
      Catalogue Number GTIN
      567333-200NMOL 04055977267211