Our broad portfolio consists of multiplex panels that allow you to choose, within the panel, analytes that best meet your needs. On a separate tab you can choose the premixed cytokine format or a single plex kit.
Cell Signaling Kits & MAPmates™
Choose fixed kits that allow you to explore entire pathways or processes. Or design your own kits by choosing single plex MAPmates™, following the provided guidelines.
The following MAPmates™ should not be plexed together:
-MAPmates™ that require a different assay buffer
-Phospho-specific and total MAPmate™ pairs, e.g. total GSK3β and GSK3β (Ser 9)
-PanTyr and site-specific MAPmates™, e.g. Phospho-EGF Receptor and phospho-STAT1 (Tyr701)
-More than 1 phospho-MAPmate™ for a single target (Akt, STAT3)
-GAPDH and β-Tubulin cannot be plexed with kits or MAPmates™ containing panTyr
.
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To begin designing your MILLIPLEX® MAP kit select a species, a panel type or kit of interest.
Custom Premix Selecting "Custom Premix" option means that all of the beads you have chosen will be premixed in manufacturing before the kit is sent to you.
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Add Additional Reagents (Buffer and Detection Kit is required for use with MAPmates)
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48-602MAG
Buffer Detection Kit for Magnetic Beads
1 Kit
Space Saver Option Customers purchasing multiple kits may choose to save storage space by eliminating the kit packaging and receiving their multiplex assay components in plastic bags for more compact storage.
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506130
Sigma-AldrichReserpine - CAS 50-55-5 - Calbiochem
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Description
Overview
Binds the vesicular monoamine transporter (VMAT2) and acts as an irreversible transport inhibitor of biogenic amines. Used as a long-lasting bioamine depleter. Prevents bioamine transport into synaptic vesicles and chromaffin granules. Used as antihypertensive and antipsychotic drugs.
Oe, T., et al. 2010. Neurosci.169, 1860. Metzger, R. et al. 2002. Eur. J. Pharmacol.456, 39. Heslop, E., et al. 1999. Neuropharmacol.38, 883. Schuldiner, S., et al. 1993. J. Biol. Chem.268, 29.
Oe, T., et al. 2010. Neurosci.169, 1860. Metzger, R. et al. 2002. Eur. J. Pharmacol.456, 39. Heslop, E., et al. 1999. Neuropharmacol.38, 883. Schuldiner, S., et al. 1993. J. Biol. Chem.268, 29.
Data Sheet
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
Binds the vesicular monoamine transporter (VMAT2) and acts as an irreversible transport inhibitor of biogenic amines. Used as a long-lasting bioamine depleter. Prevents bioamine transport into synaptic vesicles and chromaffin granules. Used as antihypertensive and antipsychotic drugs.
Form
Off-white solid
Intert gas (Yes/No)
Packaged under inert gas
CAS number
50-55-5
Chemical formula
C₃₃H₄₀N₂O₉
Structure formula
Purity
≥98% by HPLC
Solubility
DMSO (100 mM)
Storage
Protect from light +2°C to +8°C
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity
Harmful & Carcinogenic / Teratogenic
References
Oe, T., et al. 2010. Neurosci.169, 1860. Metzger, R. et al. 2002. Eur. J. Pharmacol.456, 39. Heslop, E., et al. 1999. Neuropharmacol.38, 883. Schuldiner, S., et al. 1993. J. Biol. Chem.268, 29.
