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539165 Proteasome Inhibitor Set II - Calbiochem

Overview

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539165-1SET
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      Description
      OverviewContains 5 mg of ALLN (Cat. No. 208719), 100 μg each of Epoxomicin (Cat. No. 324800), and clasto-Lactacystin β-Lactone (Cat. No. 426102). Supplied with a data sheet.
      Catalogue Number539165
      Brand Family Calbiochem®
      References
      Product Information
      FormSolid
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Targetcalpain 1, calpain 2
      Secondary targetcathepsin B, cathepsin L
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      539165-1SET 07790788051303

      Documentation

      Proteasome Inhibitor Set II - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Proteasome Inhibitor Set II - Calbiochem Certificates of Analysis

      TitleLot Number
      539165

      Brochure

      Title
      Caspases and other Apoptosis Related Tools Brochure
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision04-September-2008 RFH
      DescriptionProteasomes are large multi-subunit protease complexes, which selectively degrade intracellular proteins. A protein marked for degradation is attached to multiple molecules of ubiquitin, a 76-amino acid protein, which escorts it for rapid hydrolysis, by the 26S proteasome. The proteolytic core of this complex consists of the 20S proteasome, which contains multiple peptidase activities and has a molecular mass of ~700 kDa. Recently several potent, cell-permeable proteasome inhibitors have been developed.

      The Calbiochem® brand offers a set that includes 3 proteasome inhibitors with varying inhibtory effects.

      The table below outlines some of the physical and biological properties of these compounds.
      FormSolid
      Intert gas (Yes/No) Packaged under inert gas
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Toxicity Standard Handling