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516090 Penciclovir - CAS 39809-25-1 - Calbiochem

A carba analog of Ganciclovir. Active against several herpes viruses. Induces apoptosis effectively without exerting much genotoxicity.

Penciclovir - CAS 39809-25-1 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 2-Amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)butyl]-6H-purin-6-one

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      Overview

      Key Spec Table

      CAS #Empirical Formula
      39809-25-1C₁₀H₁₅N₅O₃
      Description
      OverviewA carba analog of Ganciclovir (Cat. No. 345700). Active against several herpes viruses (IC50 = 37.9 µM for HHV-6A and 77.8 µM for HHV-6B). Induces apoptosis effectively without exerting much genotoxicity.
      Catalogue Number516090
      Brand Family Calbiochem®
      Synonyms2-Amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)butyl]-6H-purin-6-one
      References
      ReferencesLeary, J.J., et al. 2002.Antimicrob. Agents Chemother. 46, 762.
      Amjad, M., et al. 2001. Microbiol. Immunol. 45, 233.
      Thust, R., et al. 2000. Cancer Gene Ther. 7, 107.
      Thust, R., et al. 1996. Antiviral Res. 31, 105.
      Shaw, T., et al. 1994. Antimicrob. Agents Chemother. 38, 719.
      Harnden, M.R. 1989. J. Med. Chem. 32, 1738.
      Product Information
      CAS number39809-25-1
      FormWhite solid
      Hill FormulaC₁₀H₁₅N₅O₃
      Chemical formulaC₁₀H₁₅N₅O₃
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Biological Information
      Purity≥98% by HPLC
      Safety Information
      R PhraseR: 46-60-61

      May cause heritable genetic damage.
      May impair fertility.
      May cause harm to the unborn child.
      S PhraseS: 36/37/39-45-53

      Wear suitable protective clothing, gloves and eye/face protection.
      In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
      Avoid exposure - obtain special instructions before use.
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Carcinogenic / Teratogenic
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for 6 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Global Trade Item Number
      Catalogue Number GTIN
      516090 0