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500005 Nicotinic acid

extra pure Ph Eur,BP,USP

Nicotinic acid MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Niacin, 3-Pyridinecarboxylic acid

CAS #: 59-67-6 EC Number: 200-441-0 Molar Mass: 123.11 g/mol Chemical Formula: 3-(COOH)-C₅H₄N Hill Formula: C₆H₅NO₂ Grade: Ph Eur,BP,USP
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500005
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Overview

Replacement Information

Key Spec Table

CAS #EC NumberHill FormulaChemical FormulaMolar MassGrade Value
59-67-6200-441-0C₆H₅NO₂3-(COOH)-C₅H₄N123.11 g/molPh Eur,BP,USP

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      		 Fibre carton 20 kg
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      Description
      Catalogue Number500005
      SynonymsNiacin, 3-Pyridinecarboxylic acid
      DescriptionNicotinic acid
      References
      Product Information
      CAS number59-67-6
      EC number200-441-0
      GradePh Eur,BP,USP
      Hill FormulaC₆H₅NO₂
      Chemical formula3-(COOH)-C₅H₄N
      Molar Mass123.11 g/mol
      HS Code2936 29 51
      Structure formula ImageStructure formula Image
      Quality LevelMQ400
      Applications
      Biological Information
      Physicochemical Information
      Density1.473 g/cm3 (25 °C)
      Flash point193 °C
      Ignition temperature>365 °C Dust
      Melting Point236.6 °C
      pH value3.4 (10 g/l, H₂O, 20 °C)
      Bulk density330 kg/m3
      Solubility18 g/l
      Dimensions
      Materials Information
      Toxicological Information
      LD 50 oralLD50 Rat > 5000 mg/kg
      LD 50 dermalLD50 Rat > 2000 mg/kg
      Safety Information according to GHS
      Hazard Pictogram(s) Hazard Pictogram(s)
      Hazard Statement(s)H319: Causes serious eye irritation.
      Precautionary Statement(s)P264: Wash skin thoroughly after handling.
      P280: Wear eye protection/ face protection.
      P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
      P337 + P313: If eye irritation persists: Get medical advice/ attention.
      Signal WordWarning
      Storage class10 - 13 Other liquids and solids
      WGKWGK 1 slightly hazardous to water
      Disposal4
      Liquid organic acids or solutions should be diluted, if necessary, and carefully neutralized with sodium hydrogen carbonate (Cat. No. 106323) or with sodium hydroxide (Cat. No 106462). Before filling into container D, check the pH with pH universal indicator strips (Cat. No. 109535).
      Safety Information
      Categories of dangerirritant
      Product Usage Statements
      Storage and Shipping Information
      StorageStore at +15°C to +25°C.
      Packaging Information
      Transport Information
      Declaration (railroad and road) ADR, RIDKein Gefahrgut
      Declaration (transport by air) IATA-DGRNo Dangerous Good
      Declaration (transport by sea) IMDG-CodeNo Dangerous Good
      Supplemental Information
      Specifications
      Assay (alkalimetric, calculated on dried substance)99.5 - 100.5 %
      Assay (HPLC, calculated on dried substance)98.0 - 102.0 %
      Identity (HPLC)passes test
      Identity (IR-spectrum)passes test
      Identity (Melting point)passes test
      Identity (UV-absorption)passes test
      Appearancewhite to almost white, crystalline powder
      Melting point234 - 240 °C
      Absorption ratio (A 237 / A 262)0.46 - 0.50
      Chloride (Cl)≤ 200 ppm
      Sulfate (SO₄)≤ 200 ppm
      As (Arsenic)≤ 3 ppm
      Pb (Lead)≤ 10 ppm
      Cu (Copper)*≤ 25 ppm
      Cu (Copper) (ICP)*≤ 25 ppm
      Pd (Palladium)*≤ 1 ppm
      Zn (Zinc)≤ 25 ppm
      Residual solvents (ICH Q3C)excluded by production process
      Related substances (HPLC) (largest single impurity)≤ 0.05 %
      Related substances (HPLC, Ph Eur) (sum of all impurities)≤ 0.05 %
      Related substances (HPLC) (Isocinchomeronic acid)≤ 0.05 %
      Related substances (HPLC) (6-Hydroxynicotinic acid)≤ 0.05 %
      Related substances (HPLC) (Isonicotinic acid)≤ 0.05 %
      Related substances (HPLC) (6-Methylnicotinic acid)≤ 0.05 %
      Related substances (HPLC) (6,6‘-Dinicotinic acid)≤ 0.05 %
      Related substances (HPLC) (5-Nitronicotinic acid)≤ 0.05 %
      Related substances (HPLC) (Pyridine)≤ 0.05 %
      Related substances (HPLC) (3-Nitropyridine)≤ 0.05 %
      Related substances (HPLC) (3,5-Dinitropyridine)≤ 0.05 %
      Related substances (HPLC) (3-Ethylpyridine)≤ 0.05 %
      Related substances (HPLC) (5-Ethyl-2-methylpyridine)≤ 0.05 %
      Related substances (HPLC) (any unspecified impurity)≤ 0.05 %
      Related substances (HPLC, USP) (sum of all impurities)≤ 0.20 %
      Sulfated ash (600 °C)≤ 0.1 %
      Loss on drying (105 °C, 1h)≤ 1.0 %
      Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
      Corresponds to Ph Eur, BP, USP
      Global Trade Item Number
      Catalogue Number GTIN
      5000059020 04022536255002

      Documentation

      Required Licenses

      Title
      PRODUCTO REGULADO POR LA SECRETARÍA DE SALUD

      Nicotinic acid SDS

      Title

      Safety Data Sheet (SDS) 

      Nicotinic acid Certificates of Analysis

      Product Number PackagingSpecificationLot Number
      5000059020 Fibre cartonPDF Specification Document

      Certificates

      Title