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234376 Macrophage Colony-Stimulating Factor, Human, Recombinant, E. coli

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: rhM-CSF

234376
  
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      Overview

      Replacement Information
      Description
      Overview

      This product has been discontinued.



      Recombinant, human macrophage colony-stimulating factor expressed in E. coli. Stimulates formation of macrophage colonies from bone marrow hematopoietic progenitor cells. Increases osteoclastic bone resorption in adults. Induces cell death in HIV-1 infected monocytes.
      Catalogue Number234376
      Brand Family Calbiochem®
      SynonymsrhM-CSF
      References
      ReferencesEdwards, M., et al. 1998. Bone 22, 325.
      Bergamini, A., et al. 1994. Immunol. Lett. 42, 35.
      Hattersley, G., et al. 1991. Biochem. Biophys. Res. Commun. 177, 526.
      Product Information
      CAS number81627-83-0
      FormLyophilized
      FormulationLyophilized from sterile-filtered PBS, 50 µg of BSA/µg M-CSF.
      Quality LevelMQ100
      Applications
      Biological Information
      Biological activityED₅₀ = 0.5-1.5 ng/ml as measured in a cell proliferation assay using the M-CSF-dependent mouse monocytic cell line, M-NFS-60
      Purity≥97% by SDS-PAGE
      Physicochemical Information
      ContaminantsEndotoxin: <1.0 EU/µg M-CSF
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSGI5500000
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for 1 month at 4°C or for 3 months at -70°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      234376 0

      Documentation

      Macrophage Colony-Stimulating Factor, Human, Recombinant, E. coli SDS

      Title

      Safety Data Sheet (SDS) 

      Macrophage Colony-Stimulating Factor, Human, Recombinant, E. coli Certificates of Analysis

      TitleLot Number
      234376

      References

      Reference overview
      Edwards, M., et al. 1998. Bone 22, 325.
      Bergamini, A., et al. 1994. Immunol. Lett. 42, 35.
      Hattersley, G., et al. 1991. Biochem. Biophys. Res. Commun. 177, 526.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision09-June-2008 RFH
      SynonymsrhM-CSF
      DescriptionRecombinant, human macrophage colony-stimulating factor expressed in E. coli. Stimulates formation of macrophage colonies from bone marrow hematopoietic progenitor cells. Induces cell death in HIV-1 infected monocytes. Human M-CSF is active in murine systems and the recombinant cytokine is indistinguishable from the natural M-CSF in all biological assays tested.
      FormLyophilized
      FormulationLyophilized from sterile-filtered PBS, 50 µg of BSA/µg M-CSF.
      CAS number81627-83-0
      RTECSGI5500000
      Purity≥97% by SDS-PAGE
      ContaminantsEndotoxin: <1.0 EU/µg M-CSF
      Biological activityED₅₀ = 0.5-1.5 ng/ml as measured in a cell proliferation assay using the M-CSF-dependent mouse monocytic cell line, M-NFS-60
      SolubilityReconstitute to a concentration of ≥1 mg/ml with sterile PBS containing ≥0.1% HSA or BSA.
      Storage ≤ -70°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for 1 month at 4°C or for 3 months at -70°C.
      Toxicity Standard Handling
      ReferencesEdwards, M., et al. 1998. Bone 22, 325.
      Bergamini, A., et al. 1994. Immunol. Lett. 42, 35.
      Hattersley, G., et al. 1991. Biochem. Biophys. Res. Commun. 177, 526.

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