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444278 MMP-9 Inhibitor I - CAS 1177749-58-4 - Calbiochem

Overview

Key Spec Table

CAS #Empirical Formula
1177749-58-4C₂₇H₃₃N₃O₅S

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444278-500UG
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      Plastic ampoule 500 μg
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      Description
      OverviewA cell-permeable, potent, selective, and reversible MMP-9 Inhibitor (IC50 = 5 nM). Inhibits MMP-1 (IC50 = 1.05 µM) and MMP-13 (IC50 = 113 nM) only at much higher concentrations.
      Catalogue Number444278
      Brand Family Calbiochem®
      References
      ReferencesLevin, J.I., et al. 2001. Bioorg. Med. Chem. Lett. 11, 2189.
      Product Information
      CAS number1177749-58-4
      ATP CompetitiveN
      FormOff-white solid
      Hill FormulaC₂₇H₃₃N₃O₅S
      Chemical formulaC₂₇H₃₃N₃O₅S
      ReversibleY
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Biological Information
      Primary TargetMMP-9
      Primary Target IC<sub>50</sub>5 nM
      Purity≥93% by HPLC
      Physicochemical Information
      Cell permeableY
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Global Trade Item Number
      Catalogue Number GTIN
      444278-500UG 04055977186598