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107267 L-Phenylalanine

Overview

Replacement Information

Key Spec Table

CAS #EC NumberHill FormulaMolar MassGrade Value
63-91-2200-568-1C₉H₁₁NO₂165.19 g/molPh Eur,JP,USP

Pricing & Availability

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1072671000
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      Plastic bottle 1 kg
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      1072679010
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          Plastic drum 10 kg
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          Description
          Catalogue Number107267
          SynonymsPhe, 2-Amino-3-phenylpropionic acid
          References
          Product Information
          CAS number63-91-2
          EC number200-568-1
          GradePh Eur,JP,USP
          Hill FormulaC₉H₁₁NO₂
          Molar Mass165.19 g/mol
          HS Code2922 49 90
          Structure formula ImageStructure formula Image
          Quality LevelMQ500
          Applications
          Biological Information
          Physicochemical Information
          Density1.34 g/cm3 (20 °C)
          Melting Point270 - 284 °C (decomposition)
          pH value5.0 - 7 (16.5 g/l, H₂O, 25 °C)
          Vapor pressure<1 Pa (25 °C)
          Bulk density580 kg/m3
          Solubility27 g/l
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSAY7535000
          Storage class10 - 13 Other liquids and solids
          WGKWGK 1 slightly hazardous to water
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          StorageStore at +2°C to +30°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications
          Assay (perchloric acid titration, calculated on dried substance)98.5 - 101.0 %
          Identity (IR-spectrum)passes test
          Identity (specific rotation)passes test
          Appearancewhite to almost white, crystalline powder
          Appearance of solution (50 g/l, hydrochloric acid 1 mol/l)clear and not more intense in colour than reference solution BY₆
          Spec. rotation (α 20/D, 20 g/l, water, calc. on dried substance)-33.0 to -35.5
          Spec. rotation (α 25/D, 20 g/l, water, calc. on dried substance)-32.7 to -34.7
          pH (10 g/l, CO₂-free water)5.4 - 6.0
          Chloride (Cl)≤ 200 ppm
          Sulfate (SO₄)≤ 200 ppm
          Al (Aluminium)≤ 5 ppm
          Cu(Copper)≤ 25 ppm
          Fe (Iron)≤ 10 ppm
          Mn (Manganese)≤ 25 ppm
          Related substances (TLC)passes test
          Related Compounds, total (TLC)≤ 0.5 %
          Ninhydrin-positive substances (LC) (any ninhydrin-positive impurity)≤ 0.2 %
          Ninhydrin-positive substances (LC) (ammonium (570 nm))≤ 0.02 %
          Ninhydrin-positive substances (LC) (total impurities)≤ 0.5 %
          Residual solvents (ICH Q3C)excluded by manufacturing process
          Sulfated ash (600 °C)≤ 0.1 %
          Loss on drying (105 °C; 3 h)≤ 0.30 %
          Bacterial endotoxins≤ 3.0 I.U./g
          Microbiological test (total aerobic microbial count (TAMC))≤ 10²
          Microbiological test (total yeast and mould count (TYMC))≤ 10²
          Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
          Corresponds to Ph. Eur., JP, USP
          Global Trade Item Number
          Catalogue Number GTIN
          1072671000 04022536919379
          1072679010 04022536919386

          Documentation

          Material Qualification Dossier

          TitleVersion
          8.0

          Quality Management Dossier (Open Access)

          Title

          Operational Excellence Dossier

          Title

          L-Phenylalanine SDS

          Title

          Safety Data Sheet (SDS) 

          L-Phenylalanine Certificates of Analysis

          Product Number PackagingSpecificationLot Number
          1072671000 Plastic bottlePDF Specification Document
          1072679010 Plastic drumPDF Specification Document

          Certificates

          Title

          Technical Info

          Title
          White Paper: The Viscosity Reduction Platform

          User Guides

          Title
          Raw Materials for Biopharmaceutical Manufacturing
          User Guide - Experimental Procedures to Evaluate the Viscosity Reduction Platform