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324801 InSolution™ Epoxomicin, Synthetic - Calbiochem

InSolution™ Epoxomicin, Synthetic, is a 1 mM solution of Epoxomicin, Synthetic (Cat. No. 324800) in DMSO.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Proteasome Inhibitor XIV

Primary Target: CT-L,T-L,PGPH activity of proteasome
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324801
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Overview

Replacement Information

Key Spec Table

Empirical Formula
C₂₈H₅₀N₄O₇

Pricing & Availability

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324801-50UG
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      		 Plastic ampoule 50 μg
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      Description
      Catalogue Number324801
      Brand Family Calbiochem®
      SynonymsProteasome Inhibitor XIV
      References
      ReferencesMeng, L., et al. 1999. Proc. Natl. Acad. Sci. USA 96, 10403.
      Sin, N., et al. 1999. Bioorg. Med. Chem. Lett. 9, 2283.
      Hanada, M., et al. 1992. J. Antibiot. 45, 1746.
      Product Information
      ATP CompetitiveN
      FormLiquid
      FormulationA 1 mM (50 µg/90 µl) solution of Epoxomicin, Synthetic (Cat. No. 324800) in DMSO.
      Hill FormulaC₂₈H₅₀N₄O₇
      Chemical formulaC₂₈H₅₀N₄O₇
      Hygroscopic Hygroscopic
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetCT-L,T-L,PGPH activity of proteasome
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped with Blue Ice or with Dry Ice
      Toxicity Irritant
      Storage -20°C
      Protect from Light Protect from light
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      324801-50UG 04055977216165

      Documentation

      Required Licenses

      Title
      PRODUCTO REGULADO POR LA SECRETARÍA DE SALUD

      InSolution™ Epoxomicin, Synthetic - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      InSolution™ Epoxomicin, Synthetic - Calbiochem Certificates of Analysis

      TitleLot Number
      324801

      References

      Reference overview
      Meng, L., et al. 1999. Proc. Natl. Acad. Sci. USA 96, 10403.
      Sin, N., et al. 1999. Bioorg. Med. Chem. Lett. 9, 2283.
      Hanada, M., et al. 1992. J. Antibiot. 45, 1746.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision20-June-2008 RFH
      SynonymsProteasome Inhibitor XIV
      DescriptionAn antitumor agent of microbial origin that acts as a potent, highly specific, and irreversible inhibitor of chymotrypsin-like (CT-L), trypsin-like (T-L), and peptidylglutamyl peptide hydrolyzing (PGPH) activities of the proteasome. Modifies the proteasomal catalytic subunits LMP-7, MECL1, and Z. Epoxomicin also displays potent anti-inflammatory activity in vivo.
      FormLiquid
      FormulationA 1 mM (50 µg/90 µl) solution of Epoxomicin, Synthetic (Cat. No. 324800) in DMSO.
      Intert gas (Yes/No) Packaged under inert gas
      Chemical formulaC₂₈H₅₀N₄O₇
      Structure formulaStructure formula
      Purity≥95% by HPLC
      Storage Protect from light
      -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Toxicity Irritant
      ReferencesMeng, L., et al. 1999. Proc. Natl. Acad. Sci. USA 96, 10403.
      Sin, N., et al. 1999. Bioorg. Med. Chem. Lett. 9, 2283.
      Hanada, M., et al. 1992. J. Antibiot. 45, 1746.