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324903 Epiregulin, Human, Recombinant

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324903
  
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      Overview

      Key Spec Table

      Purity
      ≥97% by SDS-PAGE
      Description
      OverviewRecombinant, human epiregulin consisting of amino acids 63-108 and expressed in E. coli with an N-terminal methionine. Epiregulin, expressed primarily in the placenta and macrophages, stimulates fibroblast, smooth muscle cell, and hepatocyte proliferation.
      Catalogue Number324903
      Brand Family Calbiochem®
      References
      ReferencesMishre, R., et al. 2002. Am. J. Physiol. Renal. Physiol. 283, F1151.
      Shirakata, Y., et al. 2000. J. Biol. Chem. 275, 5748.
      Shelly, M., et al. 1998. J. Biol. Chem. 273, 10496.
      Das, S.K., et al. 1997. Dev. Biol. 190, 178.
      Komurasaki, T., et al. 1997. Oncogene 15, 2841.
      Toyoda, H., et al. 1997. Biochem. J. 326, 69.
      Toyoda, H., et al. 1995. J. Biol. Chem. 270, 7495.
      Product Information
      FormSolid
      FormulationLyophilized from 0.2 µm sterile-filtered PBS, BSA.
      Quality LevelMQ100
      Biological Information
      Biological activityED₅₀ = 0.125-0.75 ng/ml as measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblasts.
      Purity≥97% by SDS-PAGE
      Physicochemical Information
      ContaminantsEndotoxin: <1.0 EU/µg protein
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.
      Global Trade Item Number
      Catalogue Number GTIN
      324903 0