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324413 Dynamin Inhibitor IV, Hydroxy-Dynasore - Calbiochem

The Dynamin Inhibitor IV, Hydroxy-Dynasore controls the biological activity of Dynamin. This small molecule/inhibitor is primarily used for Cell Signaling applications.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 3-Hydroxynaphthalene-2-carboxylic acid-(2,4,5-trihydroxybenzylidene)-hydrazide

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324413
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Overview

Replacement Information

Key Spec Table

Empirical Formula
C₁₈H₁₄N₂O₅

Pricing & Availability

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324413-10MG
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      		 Glass bottle 10 mg
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      Description
      OverviewA highly potent (IC50 = 0.38 and 2.6 µM for dynamin I and dynamin II, respectively), cell-permeable and in vivo bioavailable (30 mg/kg in mice, i.p.) hydroxylated analog of Dynamin Inhibitor I, Dynasore (Cat. No. 324410).
      Catalogue Number324413
      Brand Family Calbiochem®
      Synonyms3-Hydroxynaphthalene-2-carboxylic acid-(2,4,5-trihydroxybenzylidene)-hydrazide
      References
      ReferencesHarper, C.B., et al. 2011. J. Biol. Chem. 286, 35966.
      Howes, M.T., et al. 2010. J. Cell Biol. 190, 675.
      Product Information
      FormYellow solid
      Hill FormulaC₁₈H₁₄N₂O₅
      Chemical formulaC₁₈H₁₄N₂O₅
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥97% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      324413-10MG 04055977197198

      Documentation

      Dynamin Inhibitor IV, Hydroxy-Dynasore - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Dynamin Inhibitor IV, Hydroxy-Dynasore - Calbiochem Certificates of Analysis

      TitleLot Number
      324413

      References

      Reference overview
      Harper, C.B., et al. 2011. J. Biol. Chem. 286, 35966.
      Howes, M.T., et al. 2010. J. Cell Biol. 190, 675.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision21-November-2011 RFH
      Synonyms3-Hydroxynaphthalene-2-carboxylic acid-(2,4,5-trihydroxybenzylidene)-hydrazide
      DescriptionA highly potent (IC50 = 0.38 and 2.6 µM for dynamin I and dynamin II, respectively), cell-permeable and in vivo bioavailable (30 mg/kg in mice, i.p.) hydroxylated analog of Dynamin Inhibitor I, Dynasore (Cat. No. 324410).
      FormYellow solid
      Intert gas (Yes/No) Packaged under inert gas
      Chemical formulaC₁₈H₁₄N₂O₅
      Structure formulaStructure formula
      Purity≥97% by HPLC
      SolubilityDMSO (100 mg/ml)
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesHarper, C.B., et al. 2011. J. Biol. Chem. 286, 35966.
      Howes, M.T., et al. 2010. J. Cell Biol. 190, 675.