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251765 DAR-4M AM - Calbiochem

A cell-permeable, photo-stable nitric oxide (NO) fluorescent indicator with a detection limit of ~10 nM.

DAR-4M AM - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Diaminorhodamine-4M AM

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251765
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Overview

Key Spec Table

Empirical Formula
C₂₈H₃₁IN₄O₅

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251765-1MG
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      Description
      OverviewA cell-permeable, photo-stable nitric oxide (NO) fluorescent indicator with a detection limit of ~10 nM. Intracellularly releases DAR-4M (Cat. No. 251760) by the action of esterases. Reacts with NO, in the presence of O2, resulting in a triazolo-rhodamine analog (DAR-4M T) that exhibits about 840-fold greater fluorescence quantum efficiency. The fluorescence intensity is not dependent on pH.
      Catalogue Number251765
      Brand Family Calbiochem®
      SynonymsDiaminorhodamine-4M AM
      References
      ReferencesKojima, H., et al. 2001. Anal. Chem. 73, 1967.
      Kojima, H., et al. 2000. Tetrahedron Lett. 41, 69.
      Product Information
      ATP CompetitiveN
      DeclarationNot available for sale in Japan.
      FormDark red solution
      FormulationIn DMSO.
      Hill FormulaC₂₈H₃₁IN₄O₅
      Chemical formulaC₂₈H₃₁IN₄O₅
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Biological Information
      Primary TargetNitric oxide (NO) fluorescent indicator
      Purity≥98% by HPLC
      Physicochemical Information
      Cell permeableY
      Emission max.
      Excitation max.
      Safety Information
      R PhraseR: 36/37/38

      Irritating to eyes, respiratory system and skin.
      S PhraseS: 23-26-36

      Do not breathe fumes.
      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing.
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Irritant
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze at (-20°C). Use immediately after dilution, discard any unused portion.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Global Trade Item Number
      Catalogue Number GTIN
      251765-1MG 04055977217261