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227039 Cholera Toxin, B Subunit, Vibrio cholerae, Type Inaba 569B - Calbiochem

Cholera Toxin, B Subunit, Vibrio cholerae, Type Inaba 569B, CAS 9012-63-9, is responsible for toxin binding to GM1 ganglioside receptors. When used alone, it blocks toxin action on intact cells.

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227039
  
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      Overview

      Description
      Overview

      This product has been discontinued.



      Subunit of cholera toxin responsible for binding to GM1 ganglioside receptors in membranes. When used along, will block the action of toxin on intact cells.
      Catalogue Number227039
      Brand Family Calbiochem®
      References
      ReferencesMcCloskey, M.A. and Zhang, L. 2000. J. Cell. Biol. 148, 137.
      Mulhein, S.A., et al. 1989. J. Membr. Biol. 109, 21.
      Tsai, S.-C., et al. 1988. J. Biol. Chem. 263, 1768.
      Van Heynigen, S. 1982. Biosci. Rep. 2, 135.
      Mekalanos, J.J., et al. 1978. Infect. Immun. 20, 552.
      Gill, D.M. 1976. Biochemistry 15, 1242.
      Lai, C.Y., et al. 1976. J. Infect. Dis. 139, 674.
      Rappaport, R.S., et al. 1974. Infect. Immun. 9, 294.
      Craig, J.P. 1971. In Kadies, S., et al. (Eds.). Microbial Toxins. New York. Academic Press, 2A, 189.
      Product Information
      DeclarationNot available for sale outside of the United States.
      FormSolid
      FormulationLyophilized from 200 mM NaCl, 50 mM Tris-HCl, 3 mM NaN₃, 1 mM EDTA, pH 7.5.
      ReversibleN
      Quality LevelMQ100
      Applications
      ApplicationCholera Toxin, B Subunit, Vibrio cholerae, Type Inaba 569B, CAS 9012-63-9, is responsible for toxin binding to GM1 ganglioside receptors. When used alone, it blocks toxin action on intact cells.
      Biological Information
      Biological activityCholera Toxin, B Subunit is tested for its effectiveness in binding antitoxin using the antitoxin combining power assay described by Craig, J.P., et al.
      Primary TargetGM1 ganglioside receptors
      Physicochemical Information
      Cell permeableN
      Safety Information
      R PhraseR: 21/22-36/37/38

      Harmful in contact with skin and if swallowed.
      Irritating to eyes, respiratory system and skin.
      S PhraseS: 7-36/37

      Keep container tightly closed.
      Wear suitable protective clothing and gloves.
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Highly Toxic
      Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
      Storage +2°C to +8°C
      Do not freeze Yes
      Special InstructionsFollowing reconstitution, refrigerate (4°C). Stock solutions are stable for up to 6 months at 4°C. DO NOT FREEZE reconstituted solutions.
      End use certificateY
      Canadian export regulations Due to the country and/or U.S. state of origin of the animal material used in this product, this product may not be exported to Canada.
      Global Trade Item Number
      Catalogue Number GTIN
      227039 0