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219445 Cdk2 Inhibitor II - CAS 222035-13-4 - Calbiochem

The Cdk2 Inhibitor II, also referenced under CAS 222035-13-4, controls the biological activity of Cdk2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Compound 3

Primary Target: CDK2
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      Overview

      Replacement Information

      Key Spec Table

      CAS #Empirical Formula
      222035-13-4C₁₄H₁₁BrN₄O₃S
      Description
      OverviewA cell-permeable, reversible, ATP-competitive, potent and selective inhibitor of Cdk2 (IC50 = 60 nM).
      Catalogue Number219445
      Brand Family Calbiochem®
      SynonymsCompound 3
      References
      ReferencesDavis, S.T., et al. 2001. Science 291, 134.
      Product Information
      CAS number222035-13-4
      ATP CompetitiveY
      FormYellow solid
      Hill FormulaC₁₄H₁₁BrN₄O₃S
      Chemical formulaC₁₄H₁₁BrN₄O₃S
      ReversibleY
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetCDK2
      Primary Target IC<sub>50</sub>60 nM against Cdk2
      Purity≥95% by HPLC (sum of two isomers)
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      219445 0

      Documentation

      Cdk2 Inhibitor II - CAS 222035-13-4 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Cdk2 Inhibitor II - CAS 222035-13-4 - Calbiochem Certificates of Analysis

      TitleLot Number
      219445

      References

      Reference overview
      Davis, S.T., et al. 2001. Science 291, 134.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision05-April-2011 RFH
      SynonymsCompound 3
      DescriptionA cell-permeable, reversible, ATP-competitive, potent and selective inhibitor of Cdk2 (IC50 = 60 nM).
      FormYellow solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number222035-13-4
      Chemical formulaC₁₄H₁₁BrN₄O₃S
      Structure formulaStructure formula
      Purity≥95% by HPLC (sum of two isomers)
      SolubilityDMSO (5 mg/ml)
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesDavis, S.T., et al. 2001. Science 291, 134.