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205548 Caffeine - CAS 58-08-2 - Calbiochem

Caffeine, CAS 58-08-2, is a trimethylated xanthine that acts as a potent central nervous system stimulant. At higher doses, produces tachycardia.

Caffeine - CAS 58-08-2 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione

Primary Target: Potent central nervous system stimulant
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205548
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Overview

Key Spec Table

CAS #Empirical Formula
58-08-2C₈H₁₀N₄O₂

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      Description
      OverviewTrimethylated xanthine that acts as a potent central nervous system stimulant. At higher doses, produces tachycardia and interferes with the uptake and storage of Ca2+ by the sarcoplasmic reticulum in skeletal muscle. Prevents apoptosis and cell cycle effects induced by Camptothecin (Cat. No. 208925) and topotecan in HL-60 cells.
      Catalogue Number205548
      Brand Family Calbiochem®
      Synonyms3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione
      References
      ReferencesZhen, W., and Vaugha, A. T. 1995. Radiat. Res. 141, 170.
      Howell, L. L. 1993. Cancer Res. 54, 4993.
      Traganos, F., et al. 1993. Cancer Res. 53, 4613.
      Zahradnik, I., and Palade, P. 1993. Pflugers Arch. 424, 129.
      Product Information
      CAS number58-08-2
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₈H₁₀N₄O₂
      Chemical formulaC₈H₁₀N₄O₂
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      ApplicationCaffeine, CAS 58-08-2, is a trimethylated xanthine that acts as a potent central nervous system stimulant. At higher doses, produces tachycardia.
      Biological Information
      Primary TargetPotent central nervous system stimulant
      Purity≥99% by HPLC
      Physicochemical Information
      Cell permeableN
      Safety Information according to GHS
      RTECSEV6475000
      Safety Information
      R PhraseR: 22;
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Harmful
      Storage +15°C to +30°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Global Trade Item Number
      Catalogue Number GTIN
      205548-500GM 07790788048440