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208775 CaMKP Inhibitor - CAS 52789-62-5 - Calbiochem

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Ca2+/Calmodulin-dependent Protein Kinase Phosphatase Inhibitor, 1-Amino-8-naphthol-2,4-disulfonic acid, Na salt, dihydrate

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      Overview

      Replacement Information

      Key Spec Table

      CAS #Empirical Formula
      52789-62-5C₁₀H₈NNaO₇S₂ • 2H₂O
      Description
      Overview

      This product has been discontinued.



      An amino-naphthol sulfonic acid that acts as a substrate-competitive inhibitor of Ca2+/calmodulin-dependent protein kinase phosphatase (CaMKP) and its nuclear isoform CaMKP-N (IC50 = 6.4 and 6.6 µM, respectively), while exhibiting little activity against PP2B/CaN and PP2C (<10% inhibition at 10 µM).
      Catalogue Number208775
      Brand Family Calbiochem®
      SynonymsCa2+/Calmodulin-dependent Protein Kinase Phosphatase Inhibitor, 1-Amino-8-naphthol-2,4-disulfonic acid, Na salt, dihydrate
      References
      ReferencesSueyoshi, N., et al. 2007. Biochem. Biophys. Res. Commun. 363, 715.
      Product Information
      CAS number52789-62-5
      FormYellow solid
      Hill FormulaC₁₀H₈NNaO₇S₂ • 2H₂O
      Chemical formulaC₁₀H₈NNaO₇S₂ • 2H₂O
      Hygroscopic Hygroscopic
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥85% by Titration
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      S PhraseS: 22-24/25

      Do not breathe dust.
      Avoid contact with skin and eyes.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      208775 0

      Documentation

      References

      Reference overview
      Sueyoshi, N., et al. 2007. Biochem. Biophys. Res. Commun. 363, 715.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision07-October-2008 RFH
      SynonymsCa2+/Calmodulin-dependent Protein Kinase Phosphatase Inhibitor, 1-Amino-8-naphthol-2,4-disulfonic acid, Na salt, dihydrate
      DescriptionAn amino-naphthol sulfonic acid that acts as a substrate-competitive inhibitor of Ca2+/calmodulin-dependent protein kinase phosphatase (CaMKP) and its nuclear isoform CaMKP-N (IC50 = 6.4 and 6.6 µM, respectively), while exhibiting little activity against PP2B/CaN and PP2C (<10% inhibition at 10 µM).
      FormYellow solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number52789-62-5
      Chemical formulaC₁₀H₈NNaO₇S₂ • 2H₂O
      Structure formulaStructure formula
      Purity≥85% by Titration
      SolubilityH₂O (1 mg/ml)
      Storage Protect from light
      +2°C to +8°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Standard Handling
      ReferencesSueyoshi, N., et al. 2007. Biochem. Biophys. Res. Commun. 363, 715.