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SCT039 BioTracker Green H2O2 Live Cell Dye

Live cell imaging probe for detection of hydrogen peroxide (H2O2) in live cells.

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SCT039
3 x 30 nmol  
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      Overview

      Replacement Information
      Description
      Catalogue NumberSCT039
      DescriptionBioTracker Green H2O2 Live Cell Dye
      OverviewHydrogen peroxide (H2O2) is involved in therapeutic processes such as wound healing, anti-bacterial defense, stem cell proliferation, and an adaptive response in astrocytes that leads to neuronal protection. However, over-production of H2O2 exerts toxic effects on the cell and its surrounding environment. Over-production of H2O2 is connected to serious pathological conditions such as cancer, ageing, diabetes, and neurodegenerative diseases.

      BioTracker Green H2O2 live cell dye is a fluorescent probe that fluoresces upon reaction with H2O2 , but does not react with other ROS such as hydroxyradical (-OH), superoxide (O2－), hypochlorous acid (HOCl), singlet oxygen (1O2), and nitric oxide (NO). This dye is cell permeable and initially has low reactivity with H2O2 but it is quickly hydrolyzed by intracellular esterases to generate a reactive and cell impermeable product that fluoresces upon reaction with H2O2.

      Spectral Properties
      Absorbance (max): 492 nm
      Emission (max): 516 nm (Green)

      References
      Abo M et al. Development of a Highly Sensitive Fluorescence Probe for Hydrogen Peroxide. J. Am. Chem. Soc. 2011. 133, 27, 10629-10637.
      Alternate Names
      • HYDROP™
      References
      Product Information
      Detection methodFluorescence
      PresentationLyophilized
      Applications
      ApplicationLive cell imaging probe for detection of hydrogen peroxide (H2O2) in live cells.
      Key Applications
      • Cell Based Assays
      Application NotesLive cell fluorescent imaging. Green fluorescence.
      Biological Information
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssurancePurity: ≥ 90% (LC)
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStore BioTracker Green H2O2 Live Cell Dye at -20°C, desiccate and protect from light
      Note: Centrifuge vial briefly to collect contents at bottom of vial before opening.
      Packaging Information
      Material Size3 x 30 nmol
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      SCT039 04061841588252