Millipore Sigma Vibrant Logo

GF301 BDNF Protein, Human Recombinant Animal Free

The BDNF protein is a member of the NGF family of neurotrophic factors (also named neurotrophins) that are required for the differentiation & survival of specific neuronal subpopulations in both t

 More>>
BDNF Protein, Human Recombinant Animal Free MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
UniProt Number: P23560 Entrez Gene Number: NM_001709.3, NM_170731.3, NM_170732.3, NM_170733.2, NM_170734.2, NM_170735.4
View Products on Sigmaaldrich.com
GF301
10 µg  
Price could not be retrieved
Minimum Quantity is a multiple of
Maximum Quantity is
Upon Order Completion More Information
You Saved ()
 
—
Request Pricing
—
Limited Availability Limited Availability
In Stock 
Discontinued
Limited Quantities Available
Availability to be confirmed
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

       

      Contact Customer Service

      Overview

      Key Spec Table

      SourcePurity
      E. coli Product is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses
      Description
      Catalogue NumberGF301
      DescriptionBDNF Protein, Human Recombinant Animal Free
      Alternate Names
      • Brain derived neurotrophic factor
      • Abrineurin
      Background InformationBrain derived neurotrophic factor (BDNF) is a member of the NGF family of neurotrophic factors (also named neurotrophins) that are required for the differentiation and survival of specific neuronal subpopulations in both the central as well as the peripheral nervous system. The neurotrophin family is comprised of at least four proteins including NGF, BDNF, NT3, and NT4/5. BDNF mediates its neurotrophic properties by signaling through a high affinity cell surface receptor called gp145/trkB. BDNF is expressed as the C-terminal portion of a 247 amino acid polypeptide precursor, which also contains a signal sequence of 18 amino acid residue and a propeptide of 110 amino acid residues. Recombinant human BDNF is a 27.0 kDa homodimer of two 119 amino acid subunits linked by strong non-covalent interactions.
      Product Information
      Formulation
      PresentationProduct is filtered through a 0.2 micron filter before lyophilization.
      Quality LevelMQ100
      Applications
      ApplicationThe BDNF protein is a member of the NGF family of neurotrophic factors (also named neurotrophins) that are required for the differentiation & survival of specific neuronal subpopulations in both the central as well as the peripheral nervous system.
      Biological Information
      PurityProduct is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses
      SourceE. coli
      Cross ReactivityChicken, Frog, Mouse, Rat, Hamster, Guinea Pig, and Monkey
      Entrez Gene Number
      UniProt Number
      Product Usage Statements
      Quality AssuranceBioactivity assay: Determined by its ability to stimulate the proliferation of rat C6 cells. The expected ED50 for this effect is 0.5-1.0 μg/ml.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStore at -20°C for up to 6 months from date of receipt.
      Packaging Information
      Material Size10 µg
      Global Trade Item Number
      Catalogue Number GTIN
      GF301 04053252691423