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189482 Autocamtide-2 Related Inhibitory Peptide, Myristoylated - Calbiochem

The Autocamtide-2 Related Inhibitory Peptide, Myristoylated controls the biological activity of calmodulin-dependent protein kinase II. This small molecule/inhibitor is primarily used for Phosphorylat

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Synonyms: Myristoylated AIP, Myr-N-KKALRRQGAVDAL-OH

Primary Target: Calmodulin-Dependent Protein Kinase (CaM Kinase)-2
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189482
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Overview

Key Spec Table

Empirical Formula
C₇₈H₁₄₂N₂₂O₂₀

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189482-500UG
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      Description
      OverviewThis peptide corresponds to AIP (Cat. No. 189480) which has been myristoylated at the N-terminus, thus enhancing its cell-permeability.
      Catalogue Number189482
      Brand Family Calbiochem®
      SynonymsMyristoylated AIP, Myr-N-KKALRRQGAVDAL-OH
      References
      ReferencesGailly, P., et al. 1998. Cell Calcium 24, 293.
      Ishida, A., and Fujisawa, H. 1995. J. Biol. Chem. 270, 2163.
      Ishida, A., et al. 1995. Biochem. Biophys. Res. Commun. 212, 806.
      Product Information
      ATP CompetitiveN
      FormLyophilized
      FormulationSupplied as a trifluoroacetate salt.
      Hill FormulaC₇₈H₁₄₂N₂₂O₂₀
      Chemical formulaC₇₈H₁₄₂N₂₂O₂₀
      Hygroscopic Hygroscopic
      ReversibleN
      Quality LevelMQ100
      Biological Information
      Primary TargetCalmodulin-Dependent Protein Kinase (CaM Kinase)-2
      Primary Target IC<sub>50</sub>40 nM against cam Kinase-2
      Purity≥97% by HPLC
      Physicochemical Information
      Cell permeableY
      Peptide SequenceMyr-N-Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Ala-Val-Asp-Ala-Leu-OH
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Global Trade Item Number
      Catalogue Number GTIN
      189482-500UG 04055977221787