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OP02 Anti-v-Fes Rat mAb (F-113)

Anti-v-Fes Rat mAb (F-113) MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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OP02
  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityHostAntibody Type
      H, M, RRMonoclonal Antibody
      Description
      Overview

      This product has been discontinued.



      Recognizes with the v-Fes (feline sarcoma) domain common to the Gardner and Snyder-Thelien FeSv polyprotein translation products and mammalian p93c-fes.

    • Antibody Target Gene Symbol: ABL1
    • Target Synonym: ABL, AI325092, bcr/abl, C-ABL, C-ABL 1B, CABL1, E430008G22Rik, JTK7, MGC117749, p145Abl, p150, v-abl
    • Entrez Gene Name: c-abl oncogene 1, receptor tyrosine kinase
    • Hu Entrez ID: 25

    • Mu Entrez ID: 11350
    • Rat Entrez ID: 311860
      		•
      Catalogue NumberOP02
      Brand Family Calbiochem®
      References
      ReferencesYu, Gang, et al. 1989. J. Biol. Chem. 264, 10276.
      Harper, M.E., et al. 1983. Nature 304, 169.
      Dalla-Favera, R., et al. 1982. Proc. Natl. Acad. Sci. 79, 4714.
      Groffen, J., et al. 1982. Science 216, 1136.
      Veronese, F., et al. 1982. J. Virol. 43, 896.
      Barbacid, M., et al. 1980. Proc. Natl. Acad. Sci. 77, 5158.
      Sherr, C.J., et al. 1980. J. Virol. 34, 200.
      van de Ven, W.J.M., et al. 1980. Virology 101, 185.
      Product Information
      FormLiquid
      FormulationIn 0.05 M sodium phosphate buffer, 0.2% gelatin, pH 7.5.
      Negative controlFRE cells
      Positive controlSTFeSVFRECI 10 cells
      Preservative≤0.1% sodium azide
      Quality LevelMQ100
      Applications
      Application ReferencesOriginal Clone, Neutralization Studies Veronese, F., et al. 1982. J. Virol. 43, 896.
      Key Applications Immunoprecipitation
      Neutralization Studies
      Application NotesImmunoprecipitation (1-2 µg/sample)
      Neutralization (see application references)
      Application CommentsTo immunoprecipitate, use goat anti-rat Ig with protein G or rabbit anti-rat Ig in conjunctuction with protein A. This antibody will inhibit protein tyrosine kinase activity (see application references). Antibody should be titrated for optimal results in individual Systems.
      Biological Information
      Immunogenv-Fes-transformed cells
      CloneF-113
      HostRat
      IsotypeIgM
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Antibody TypeMonoclonal Antibody
      Concentration Label Please refer to vial label for lot-specific concentration
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Blue Ice Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Do not freeze Yes
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      OP02 0

      Documentation

      Anti-v-Fes Rat mAb (F-113) SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-v-Fes Rat mAb (F-113) Certificates of Analysis

      TitleLot Number
      OP02

      References

      Reference overview
      Yu, Gang, et al. 1989. J. Biol. Chem. 264, 10276.
      Harper, M.E., et al. 1983. Nature 304, 169.
      Dalla-Favera, R., et al. 1982. Proc. Natl. Acad. Sci. 79, 4714.
      Groffen, J., et al. 1982. Science 216, 1136.
      Veronese, F., et al. 1982. J. Virol. 43, 896.
      Barbacid, M., et al. 1980. Proc. Natl. Acad. Sci. 77, 5158.
      Sherr, C.J., et al. 1980. J. Virol. 34, 200.
      van de Ven, W.J.M., et al. 1980. Virology 101, 185.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision01-October-2007 RFH
      ApplicationImmunoprecipitation (1-2 µg/sample)
      Neutralization (see application references)
      DescriptionPurified rat monoclonal antibody generated by immunizing rats with the specified immunogen and fusing splenocytes with Y3 Ag 1.2.3 rat myeloma cells (see application references). Recognizes the v-fes encoded sequences common to the polyprotein translational products of the Snyder-Theilen and Gardner strains of feline sarcoma virus (FesV).
      BackgroundThe Snyder-Theilen and Gardner strains of feline salcoma virus (Fesv) consist of amino terminal domains of viral origin and carboxy terminal v-fes specific domains with protein-tyrosine kinase activity. The v-fes human cellular homolog, c-fes, has been cloned and mapped to band q25-q26 on chromosome 15.
      HostRat
      Immunogenv-Fes-transformed cells
      CloneF-113
      IsotypeIgM
      Specieshuman, mouse, rat
      Positive controlSTFeSVFRECI 10 cells
      Negative controlFRE cells
      FormLiquid
      FormulationIn 0.05 M sodium phosphate buffer, 0.2% gelatin, pH 7.5.
      Concentration Label Please refer to vial label for lot-specific concentration
      Preservative≤0.1% sodium azide
      CommentsTo immunoprecipitate, use goat anti-rat Ig with protein G or rabbit anti-rat Ig in conjunctuction with protein A. This antibody will inhibit protein tyrosine kinase activity (see application references). Antibody should be titrated for optimal results in individual Systems.
      Storage +2°C to +8°C
      Do Not Freeze Yes
      Toxicity Standard Handling
      ReferencesYu, Gang, et al. 1989. J. Biol. Chem. 264, 10276.
      Harper, M.E., et al. 1983. Nature 304, 169.
      Dalla-Favera, R., et al. 1982. Proc. Natl. Acad. Sci. 79, 4714.
      Groffen, J., et al. 1982. Science 216, 1136.
      Veronese, F., et al. 1982. J. Virol. 43, 896.
      Barbacid, M., et al. 1980. Proc. Natl. Acad. Sci. 77, 5158.
      Sherr, C.J., et al. 1980. J. Virol. 34, 200.
      van de Ven, W.J.M., et al. 1980. Virology 101, 185.
      Application referencesOriginal Clone, Neutralization Studies Veronese, F., et al. 1982. J. Virol. 43, 896.