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ABN23 Anti-mHUMMR Antibody

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ABN23
100 µg  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      MWBRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABN23
      DescriptionAnti-mHUMMR Antibody
      Alternate Names
      • Hypoxia up-regulated mitochondrial movement regulator
      Background InformationHypoxia up-regulated mitochondrial movement regulator (HUMMR), a novel mitochondria protein, is expressed in neurons and is markedly induced by hypoxia-inducible factor 1 α (HIF-1α). HUMMR interacts with Miro-1 and Miro-2, mitochondrial proteins that are critical for mediating mitochondrial transport. Knockdown of HUMMR or HIF-1 function in neurons exposed to hypoxia markedly reduces mitochondrial content in axons.
      References
      Product Information
      FormatAffinity Purified
      Control
      • Mouse testis lysate
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-mHUMMR Antibody is an antibody against mHUMMR for use in WB.
      Key Applications
      • Western Blotting
      Biological Information
      ImmunogenLinear peptide corresponding to mouse HUMMR.
      Epitope Unknown
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityThis antibody recognizes mouse HUMMR protein
      Species Reactivity
      • Mouse
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • HUMMR
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~ 45 kDa observed. 50 kDa calculated.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in mouse testis lysate.

      Western Blot Analysis: 1 µg/mL of this antibody detected HUMMR on 10 µg of mouse testis lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABN23 04053252412738