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ABC477 Anti-YY1AP1 Antibody

This Anti-YY1AP1 antibody is validated for use in WB, IH for the detection of YY1AP1.

Anti-YY1AP1 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: YY1AP1, HCCA2, YY1AP
UniProt Number: Q9H869
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ABC477
100 µg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, RWB, IHCRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABC477
      DescriptionAnti-YY1AP1 Antibody
      Alternate Names
      • YY1-associated protein 1
      • Hepatocellular carcinoma susceptibility protein
      • Hepatocellular carcinoma-associated protein 2
      Background InformationYY1-associated protein 1 (YY1AP1), also known as Hepatocellular carcinoma susceptibility protein, Hepatocellular carcinoma-associated protein 2, is encoded by the gene name YY1AP1, HCCA2, and YY1AP. YY1AP1 has been demonstrated to enhance transcription activation by interacting with YY1. Recent studies have shown that YY1AP1 may play a role in cell cycle regulation. YY1AP1 interacts with YY1 and MAD2L2. YY1AP1 is expressed ubiquitously. YY1AP1 has been detected in small intestine, skeletal muscle, lung, pancreas, brain, stomach, spleen, colon and heart. At very low levels, YY1AP1 has been detected in healthy liver. YY1AP1 is highly expressed in most liver carcinomas.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-YY1AP1 antibody is validated for use in WB, IH for the detection of YY1AP1.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesWestern Blotting Analysis: 0.5 µg/mL from a representative lot detected YY1AP1 in 10 µg of C2C12, Hek293, HeLa, HepG2, human placenta, Huvec, Jurkat, L6, mouse brain, NIH-3T3, PC12, PC3, and Raw 264.7 lysate.
      Immunohistochemistry Analysis: A 1:50-250 dilution from a representative lot detected YY1AP1 in human cerebellum, mouse hindbrain, and mouse cerebellum tissue.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human YY1AP1 near the N-terminal.
      EpitopeNear N-terminal
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Species Reactivity NoteHuman, Mouse, Rat. Predicted to react with Chimpanzee based on 100% sequence homology.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • YY1AP1
      • HCCA2
      • YY1AP
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~90 kDa observed. The endogenous YY1AP protein signal is found at 90 kDa, in agreement with the predicted protein size of 750 amino acids derived from open reading frame (Wang, C.Y., et al. (2004). J. Biol. Chem. 279:17750-17755).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in A431 cell lysate.

      Western Blotting Analysis: 0.5 µg/mL of this antibody detected YY1AP1 in 10 µg of A431 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABC477 04055977122152