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ABT189 Anti-Tropomyosin 4 Antibody

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ABT189
100 µL  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, RWB, IH(P)RbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABT189
      DescriptionAnti-Tropomyosin 4 Antibody
      Alternate Names
      • Tropomyosin alpha-4 chain
      • TM30p1
      • Tropomyosin-4
      Background InformationTropomyosin-4 is also called Tropomyosin alpha-4 chain and TM30p1. Tropomyosin-4 binds calcium and to actin filaments in muscle and non-muscle cells. Tropomyosin-4 associates with the troponin complex, and plays a role in the regulation of smooth and striated muscle contraction, as well as the stabilization of cytoskeleton actin filaments in non-muscle cells. Tropomyosin-4 is found in cardiac tissue and platelets.
      References
      Product Information
      FormatAffinity Purified
      Control
      • NIH/3T3 cell lysate
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-Tropomyosin 4 Antibody is an antibody against Tropomyosin 4 for use in western blotting & IHC (Paraffin).
      Key Applications
      • Western Blotting
      • Immunohistochemistry (Paraffin)
      Application NotesImmunohistochemistry Analysis: A 1:100 dilution from a representative lot detected Tropomyosin 4 in human prostate cancer sections and human heart sections tissue.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to the C-terminus of human Tropomyosin 4.
      EpitopeC-terminus
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityThis antibody recognizes the C-terminus of Tropomyosin 4.
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Species Reactivity NoteDemonstrated to react with Human, Mouse, and Rat. Predicted to react with Bovine based on 100% sequence homology.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • TPM4
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~33 kDa observed. The calculated molecular weight is 29 kDa, however Tropomyosin 4 has been shown as a ~33 kDa band in western blots (Brooke, K., et al. (2006). Bone. 39:697-705).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in NIH/3T3 cell lysate.

      Western Blotting Analysis: A 1:2,500 dilution of this antibody detected Tropomyosin 4 in 10 µg of NIH/3T3 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABT189 04053252916090

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies