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MAB8599 Anti-RSV Antibody, fusion protein, all type A, B strains, clone 131-2A

Anti-RSV Antibody, fusion protein, all type A, B strains, clone 131-2A detects level of Respiratory Syncytial Virus & has been published & validated for use in ELISA, FC, IF & WB.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Infectious Diseases Research Sub-Category: Infectious Diseases - Viral
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MAB8599
100 µg  
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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HELISA, FC, IF, WBMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMAB8599
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-RSV Antibody, fusion protein, all type A, B strains, clone 131-2A
      Alternate Names
      • RSV Fusion
      Background InformationRSV is a labile paramyxovirus that produces a characteristic fusion of human cells in tissue culture--the syncytial effect. Two subtypes, A and B, have been identified. Subtype B are characterized as the asymptomatic strains of the virus. The more severe clinical illnesses involve Subtype A strains.
      References
      Product Information
      FormatPurified
      HS Code3002 15 90
      Control
      • RSV Control Slides, Catalogue Number 5012-5
      PresentationProtein A Purified immunoglobulin in 0.02M phosphate, 0.25M NaCl, 0.1% NaN3 pH 7.6
      Quality LevelMQ300
      Applications
      ApplicationAnti-RSV Antibody, fusion protein, all type A, B strains, clone 131-2A detects level of Respiratory Syncytial Virus & has been published & validated for use in ELISA, FC, IF & WB.
      Key Applications
      • ELISA
      • Flow Cytometry
      • Immunofluorescence
      • Western Blotting
      Application NotesIndirect immunofluorescence.

      ELISA

      Immunoblotting: (using purified F protein preparations, clone identified a ~70kDa band, Tripp, RA et al 2003)

      Final working dilutions must be determined by end user.
      Biological Information
      ImmunogenA2 RSV virus cell extract
      Epitopeall type A & B strains
      Clone131-2A
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      SpecificityReacts with RSV fusion protein, specifically epitope F1a of RSV F-protein {Sominina AA, et al Vestn Ross Akad Med Nauk. 1995;(9):49-54} found on all A & B strains of RSV.
      IsotypeIgG2aκ
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Purification MethodProtein A Purfied
      Molecular Weight~70 kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain for 1 year at 2–8°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MAB8599 04053252316654

      Documentation

      Anti-RSV Antibody, fusion protein, all type A, B strains, clone 131-2A SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-RSV Antibody, fusion protein, all type A, B strains, clone 131-2A Certificates of Analysis

      TitleLot Number
      MOUSE ANTI-RSV FUSION PROTEIN MONOCLONAL ANTIBODY - 2382151 2382151
      MOUSE ANTI-RSV FUSION PROTEIN MONOCLONAL ANTIBODY - 2441924 2441924
      MOUSE ANTI-RSV FUSION PROTEIN MONOCLONAL ANTIBODY - 2453211 2453211
      MOUSE ANTI-RSV FUSION PROTEIN MONOCLONAL ANTIBODY - 2153026 2153026
      MOUSE ANTI-RSV FUSION PROTEIN - 3213889 3213889
      MOUSE ANTI-RSV FUSION PROTEIN - 3235652 3235652
      MOUSE ANTI-RSV FUSION PROTEIN - 3599028 3599028
      MOUSE ANTI-RSV FUSION PROTEIN - 3703220 3703220
      MOUSE ANTI-RSV FUSION PROTEIN - 3778051 3778051
      MOUSE ANTI-RSV FUSION PROTEIN - 3843755 3843755
      Show more

      References

      Reference overviewApplicationPub Med ID
      Real-time detection of virus particles and viral protein expression with two-color nanoparticle probes
      Agrawal, Amit, et al
      J Virol, 79:8625-8 (2005)  2005

      		Flow Cytometry15956604 15956604
      Anti-G protein antibody responses to respiratory syncytial virus infection or vaccination are associated with inhibition of G protein CX3C-CX3CR1 binding and leukocyte chemotaxis
      Harcourt, Jennifer L, et al
      J Infect Dis, 190:1936-40 (2004)  2004

      		15529257 15529257
      The G glycoprotein of respiratory syncytial virus depresses respiratory rates through the CX3C motif and substance P
      Tripp, Ralph A, et al
      J Virol, 77:6580-4 (2003)  2003

      		Immunoblotting (Western)12743318 12743318
      Involvement of toll-like receptor 4 in innate immunity to respiratory syncytial virus
      Haynes, L M, et al
      J Virol, 75:10730-7 (2001)  2001

      		Immunofluorescence11602714 11602714
      Respiratory syncytial virus G and/or SH protein alters Th1 cytokines, natural killer cells, and neutrophils responding to pulmonary infection in BALB/c mice
      Tripp, R A, et al
      J Virol, 73:7099-107 (1999)  1999

      		10438795 10438795
      Characteristics of monoclonal antibodies to RS virus in immunoenzyme and immunofluorescence techniques
      Sominina, A A, et al
      Vestn Akad Med Nauk SSSR, :49-54 (1995)  1995

      		7580416 7580416
      Subgrouping of respiratory syncytial virus strains from Australia and Papua New Guinea by biological and antigenic characteristics
      Hierholzer, J C, et al
      Arch Virol, 136:133-47 (1994)  1994

      		Enzyme Immunoassay (ELISA)8002781 8002781