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MAB5296 Anti-Oxytocin Antibody, clone 4G11

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MAB5296
100 µL  
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      Overview

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, RELISA, IHCMAscitesMonoclonal Antibody
      Description
      Catalogue NumberMAB5296
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Oxytocin Antibody, clone 4G11
      Product Information
      FormatAscites
      Control
      • Pituitary Gland
      PresentationAscites fluid without any preservative.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-Oxytocin Antibody, clone 4G11 is validated for use in ELISA, IH for the detection of Oxytocin.
      Key Applications
      • ELISA
      • Immunohistochemistry
      Application NotesImmunohistochemistry on 4% paraformaldehyde fixed frozen tissue: 1:5,000-1:10,000.

      ELISA: 1:1,000,000

      Optimal working dilutions must be determined by the end user.
      Biological Information
      ImmunogenOxytocin conjugated to thyroglobulin.
      Clone4G11
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      SpecificityRecognizes Oxytocin. No reactivity to arginine vasopressin, vasotocin or [Asu1,6,Arg8]-vasopressin by competitive ELISA.
      IsotypeIgG1
      Species Reactivity
      • Human
      • Rat
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryThere are two proteins encoded by this gene, oxytocin and neurophysin I. Oxytocin is posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions.
      Gene Symbol
      • OXT
      • MGC126890
      • MGC126892
      • OT
      • OT-NPI
      Purification MethodUnpurified
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P01178 # Oxytocin causes contraction of the smooth muscle of the uterus and of the mammary gland.
      SIZE: 125 amino acids; 12722 Da
      SUBCELLULAR LOCATION: Secreted.
      SIMILARITY: SwissProt: P01178 ## Belongs to the vasopressin/oxytocin family.
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
      Packaging Information
      Material Size100 µL
      Global Trade Item Number
      Catalogue Number GTIN
      MAB5296 04053252266683