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MABE268 Anti-Musashi-1 Antibody, clone 7B11.1

Use Anti-Musashi-1 Antibody, clone 7B11.1 (Mouse Monoclonal Antibody) validated in WB, IHC to detect Musashi-1 also known as RNA-binding protein Musashi homolog 1.

Anti-Musashi-1 Antibody, clone 7B11.1 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Epigenetics & Nuclear Function Research Sub-Category: Neural Stem Cells Gene Symbol: MSI1 UniProt Number: O43347
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MABE268
100 µg  
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      Overview

      Replacement Information

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, RWB, IHCMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABE268
      Replaces03-114; 04-1041
      DescriptionAnti-Musashi-1 Antibody, clone 7B11.1
      Alternate Names
      • RNA-binding protein Musashi homolog 1
      Background InformationIn mammals, the Musashi family is important for cell fate determination, playing roles in maintenance of the stem-cell state, cellular differentiation, nuclear signaling and tumorigenesis. Musashi-1 (also known as Msi1), is selectivley expressed in neural progenitor cells, including neural stem cells. Outside the nervous system, Musashi-1 is a selective marker for intestinal stem or early lineage cells. Musashi-1 interacts with the Notch pathway during asymmetric cell division by binding the 3' UTR of Numb. Numb is prevented from repressing Notch signaling when Musashi-1 is present.
      References
      Product Information
      FormatPurified
      Control
      • Mouse E17 spinal cord tissue lysate.
      PresentationPurified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationUse Anti-Musashi-1 Antibody, clone 7B11.1 (Mouse Monoclonal Antibody) validated in WB, IHC to detect Musashi-1 also known as RNA-binding protein Musashi homolog 1.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesWestern Blot Analysis: A representative lot detected Musashi-1 in HEK293, NIH/3T3, and PC-12 cell lysate.

      Immunohistochemistry Analysis: A 1:1,000 dilution of this antibody detected Musashi-1 in mouse cerebellum, normal mouse brain, and normal human pons tissue.
      Biological Information
      ImmunogenGST-tagged recombinant protein corresponding to human Musashi-1.
      Clone7B11.1
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      IsotypeIgG2aκ
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • MSI1
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~39 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in mouse E17 spinal cord tissue lysate.

      Western Blot Analysis: 1 µg/mL of this antibody detected Musashi-1 in 10 µg of mouse E17 spinal cord tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MABE268 04053252440434

      Documentation

      Anti-Musashi-1 Antibody, clone 7B11.1 SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Musashi-1 Antibody, clone 7B11.1 Certificates of Analysis

      TitleLot Number
      Anti-Musashi-1, clone 7B11.1 2485876
      Anti-Musashi-1, clone 7B11.1 - 2389951 2389951
      Anti-Musashi-1, clone 7B11.1 - 2460979 2460979
      Anti-Musashi-1, clone 7B11.1 - 2464645 2464645
      Anti-Musashi-1, clone 7B11.1 - 3284330 3284330
      Anti-Musashi-1, clone 7B11.1 - 3385845 3385845
      Anti-Musashi-1, clone 7B11.1 - 3918063 3918063
      Anti-Musashi-1, clone 7B11.1 - 4150407 4150407
      Anti-Musashi-1, clone 7B11.1 - Q2017859 Q2017859
      Anti-Musashi-1, clone 7B11.1 -2571254 2571254
      Show more

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies