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ABS311 Anti-LCN13 Antibody

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ABS311
100 µL  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      MWBRbSerumPolyclonal Antibody
      Description
      Catalogue NumberABS311
      DescriptionAnti-LCN13 Antibody
      Alternate Names
      • orant-binding protein 2a
      • Epididymal-specific lipocalin-13
      Background InformationEpididymal-specific lipocalin-13 (LCN13) is also called Odorant-binding protein 2a (Obp2a). LCN13 is a secreted protein that is thought to act as a retinoid carrier protein within the epididymis, and have a role in male fertility. LCN13 is expressed in the epididymis.
      References
      Product Information
      FormatSerum
      Control
      • Mouse skin tissue lysate
      PresentationRabbit polyclonal serum with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationDetect Lipocalin using this rabbit polyclonal antibody, Anti-LCN13 Antibody validated for use in western blotting.
      Key Applications
      • Western Blotting
      Application NotesWestern Blotting Analysis: A 1:1,000 dilution from a representative lot detected LCN13 in mouse lung tissue lysate.

      Western Blotting Analysis: A representative lot from an independent laboratory detected LCN13 in liver, muscle, and pancreas tissues, but not in white adipose tissue, from LCN13 transgenic male mice (Cho, K. W., et al. (2011). Mol Cell Biol. 31(3):450-7.).

      Western Blotting Analysis: A representative lot from an independent laboratory detected LCN13 in transfected mouse primary hepotcytes cell lysates (Sheng, L, et al. (2011). J Biol Chem. 286(44):38128-38135.).

      Western Blotting Analysis: A representative lot detected LCN13 in mouse adipocyte cell lysates and in certain mouse organ tissues lysates (Zhou, Y. and Rui, L., (2013). Vitam Horm. 91:369-383.).
      Biological Information
      ImmunogenRecombinant protein corresponding to mouse LCN13.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityThis antibody detects two observed isoforms of LCN13.
      Species Reactivity
      • Mouse
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • Obp2a
      • Lcn13
      Purification MethodUnpurified
      UniProt Number
      Molecular Weight~20 kDa observed. Two observed isoforms at ~20 kDa and ~28 kDa are likely due to proteolytic cleavage of a common LCN13 precursor (Cho, K. W., et al. (2011). Mol Cell Biol. 31(3):450-7.). Uncharacterized band(s) may be observed in some cell lysates.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in mouse skin tissue lysate.

      Western Blotting Analysis: A 1:1,000 dilution of this antibody detected LCN13 in 10 µg of LCN13 mouse skin tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABS311 04053252916724

      Documentation

      Required Licenses

      Title
      PRODUCTO REGULADO POR LA SECRETARÍA DE SALUD

      Anti-LCN13 Antibody SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-LCN13 Antibody Certificates of Analysis

      TitleLot Number
      Anti-LCN13 - 3819087 3819087
      Anti-LCN13 - Q2218167 Q2218167

      References

      Reference overviewPub Med ID
      Lipocalin 13 regulation of glucose and lipid metabolism in obesity.
      Zhou, Yingjiang and Rui, Liangyou
      Vitam. Horm., 91: 369-83 (2013)  2013

      Show Abstract
      23374724 23374724
      Lipocalin 13 protein protects against hepatic steatosis by both inhibiting lipogenesis and stimulating fatty acid β-oxidation.
      Sheng, Liang, et al.
      J. Biol. Chem., 286: 38128-35 (2011)  2011

      Show Abstract
      21908604 21908604
      Lipocalin-13 regulates glucose metabolism by both insulin-dependent and insulin-independent mechanisms.
      Cho, Kae Won, et al.
      Mol. Cell. Biol., 31: 450-7 (2011)  2011

      Show Abstract
      21135134 21135134