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420293 Anti-IRS-2 (1122-1321) Rabbit pAb

Anti-IRS-2 (1122-1321) Rabbit pAb MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Anti-Insulin Receptor Substrate 2

420293
  
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      Overview

      Replacement Information

      Key Spec Table

      Host
      Rb
      Description
      Overview

      This product has been discontinued.



      Please refer to our complete listing of IRS antibodies for possible alternatives.






      Recognizes the ~180 kDa IRS-2 protein.
      Catalogue Number420293
      Brand Family Calbiochem®
      SynonymsAnti-Insulin Receptor Substrate 2
      References
      ReferencesZhande, R., et al. 2002. Mol. Cell Biol. 22, 1016.
      Qiao, L., et al. 1999. J. Biol. Chem. 274, 10625.
      Sun, X.J., et al. 1999. Diabetes 48, 1359.
      Product Information
      FormLiquid
      FormulationUndiluted serum.
      PreservativeNone
      Applications
      Key Applications Immunoblotting (Western Blotting)
      Immunoprecipitation
      Application NotesImmunoblotting (1:500)
      Immunoprecipitation (1:200)
      Application CommentsDoes not cross-react with IRS-1. Variables associated with assay conditions will dictate the proper working dilution.
      Biological Information
      Immunogena recombinant protein containing amino acids 1122-1321 of mouse IRS-2 fused to GST
      ImmunogenMouse
      HostRabbit
      IsotypeIgG
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage -20°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      420293 0

      Documentation

      Anti-IRS-2 (1122-1321) Rabbit pAb Certificates of Analysis

      TitleLot Number
      420293

      References

      Reference overview
      Zhande, R., et al. 2002. Mol. Cell Biol. 22, 1016.
      Qiao, L., et al. 1999. J. Biol. Chem. 274, 10625.
      Sun, X.J., et al. 1999. Diabetes 48, 1359.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision12-October-2007 JSW
      SynonymsAnti-Insulin Receptor Substrate 2
      ApplicationImmunoblotting (1:500)
      Immunoprecipitation (1:200)
      DescriptionRabbit polyclonal antibody supplied as undiluted serum. Recognizes the ~180 kDa IRS-2 protein.
      BackgroundUpon insulin stimulation, IRS proteins are phosphorylated by insulin receptor tyrosine kinase. Decreased levels of IRS proteins are associated with insulin resistance in humans. IRS-2 can serve as an alternative insulin substrate in IRS-1 deficient mice.
      HostRabbit
      Immunogen speciesMouse
      Immunogena recombinant protein containing amino acids 1122-1321 of mouse IRS-2 fused to GST
      IsotypeIgG
      Specieshamster, human, mouse, rat
      FormLiquid
      FormulationUndiluted serum.
      PreservativeNone
      CommentsDoes not cross-react with IRS-1. Variables associated with assay conditions will dictate the proper working dilution.
      Storage Avoid freeze/thaw
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Toxicity Standard Handling
      ReferencesZhande, R., et al. 2002. Mol. Cell Biol. 22, 1016.
      Qiao, L., et al. 1999. J. Biol. Chem. 274, 10625.
      Sun, X.J., et al. 1999. Diabetes 48, 1359.