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MAB2153 Anti-E-Selectin Antibody, lectin domain, clone UZ4

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MAB2153
100 µg  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, MELISA, FC, IP, WB, FUNCRPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMAB2153
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-E-Selectin Antibody, lectin domain, clone UZ4
      Alternate Names
      • CD62E
      • ELAM-1
      References
      Product Information
      FormatPurified
      Quality LevelMQ100
      Applications
      ApplicationAnti-E-Selectin Antibody, lectin domain, clone UZ4 is an antibody against E-Selectin for use in ELISA, FC, IP & WB.
      Key Applications
      • ELISA
      • Flow Cytometry
      • Immunoprecipitation
      • Western Blotting
      • Affects Function
      Applications Not Recommended
      • Immunohistochemistry
      Biological Information
      ImmunogenIgM
      Epitopelectin domain
      CloneUZ4
      HostRat
      Species Reactivity
      • Human
      • Mouse
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryThe endothelial leukocyte adhesion molecule-1 is expressed by cytokine-stimulated endothelial cells. It is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. This gene is present in single copy in the human genome and contains 14 exons spanning about 13 kb of DNA. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis.
      Gene Symbol
      • SELE
      • LECAM2
      • ESEL
      • ELAM
      • ELAM-1
      • CD62E
      • ELAM1
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P16581 # Expressed on cytokine induced endothelial cells and mediates their binding to leukocytes. The ligand recognized by ELAM-1 is sialyl-lewis X (alpha(1->3)fucosylated derivatives of polylactosamine that are found at the nonreducing termini of glycolipids).
      SIZE: 610 amino acids; 66655 Da
      SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
      SIMILARITY: SwissProt: P16581 ## Belongs to the selectin/LECAM family. & Contains 1 C-type lectin domain. & Contains 1 EGF-like domain. & Contains 6 Sushi (CCP/SCR) domains.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MAB2153 04053252576430

      Documentation

      Anti-E-Selectin Antibody, lectin domain, clone UZ4 SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-E-Selectin Antibody, lectin domain, clone UZ4 Certificates of Analysis

      TitleLot Number
      RAT ANTI-E-SELECTIN 2479817
      RAT ANTI-E-SELECTIN MONOCLONAL ANTIBODY - 2111257 2111257
      RAT ANTI-E-SELECTIN MONOCLONAL ANTIBODY - 2462906 2462906
      RAT ANTI-E-SELECTIN - 3484047 3484047
      RAT ANTI-E-SELECTIN -2666614 2666614
      RAT ANTI-E-SELECTIN -2751153 2751153
      RAT ANTI-E-SELECTIN -2766374 2766374
      RAT ANTI-E-SELECTIN MONOCLONAL ANTIBODY 2981017
      RAT ANTI-E-SELECTIN MONOCLONAL ANTIBODY - 3174772 3174772

      Data Sheet

      Title
      RAT ANTI-E-SELECTIN MONOCLONAL ANTIBODY

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies