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MAB2053 Anti-Disialoganglioside GD3 Antibody, clone MB3.6

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MAB2053
100 µg  
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      Overview

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HFC, IF, IHCMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMAB2053
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Disialoganglioside GD3 Antibody, clone MB3.6
      Product Information
      FormatPurified
      PresentationLiquid in 0.02M PB pH 7.6, 0.25M NaCl containing 0.1% NaN3.
      Quality LevelMQ100
      Applications
      ApplicationAnti-Disialoganglioside GD3 Antibody, clone MB3.6 is an antibody against Disialoganglioside GD3 for use in FC, IF, IH.
      Key Applications
      • Flow Cytometry
      • Immunofluorescence
      • Immunohistochemistry
      Application NotesImmunohistochemistry (frozen tissue sections)

      Immunofluorescence of cells in culture

      Flow cytometry: 1-2 μg per 10E6 cells

      Lysis of GD3 positive (melanoma) cells in presence of complement (Cheresh et al., 1985).

      Induction of antibody dependent cellular cyotoxicity (ADCC) {Ortaldo JR et al 1987 J Immunol 138(10):3566-3572.

      TLC analysis: Sjoberg, ER (1995) J. Biol. Chem. 270(7):2921-2930.{http://www.jbc.org/cgi/content/full/270/7/2921}





      Optimal working dilutions must be determined by end user.
      Biological Information
      ImmunogenFM9 melanoma cells
      CloneMB3.6
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      SpecificityReacts specifically with human GD3 ganglioside (Cheresh et al., 1984). No cross-reactivity with other gangliosides purified from neuroblastoma or melanoma cells.
      IsotypeIgG3
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at 2-8°C in undiluted aliquots for up to 6 months.
      Packaging Information
      Material Size100 µg
      Global Trade Item Number
      Catalogue Number GTIN
      MAB2053 04053252728174