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ABT274 Anti-Decorin Antibody

Anti-Decorin Antibody is an antibody against Decorin for use in Immunohistochemistry, Western Blotting.

Anti-Decorin Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Cell Structure Research Sub-Category: Adhesion (CAMs) Gene Symbol: Dcn UniProt Number: P28654
ABT274
200 µL  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      MIHC, WBRbSerumPolyclonal Antibody
      Description
      Catalogue NumberABT274
      DescriptionAnti-Decorin Antibody
      Alternate Names
      • Decorin
      • Bone proteoglycan II
      • PG-S2
      • PG40
      Background InformationDecorin (UniProt P28654; also known as Bone proteoglycan II, PG40, PG-S2) is encoded by the Dcn (also known as DC, DSPG2, mDcn, PGII, SLRR1B) gene (Entrez Gene ID 13179) in murine. Decorin is a pericellular matrix proteoglycan structurally related to two other small proteoglycans, biglycan and fibromodulin. Decorin and biglycan are thought to be the result of a gene duplication. Decorin contains one attached glycosaminoglycan chain, while biglycan contains two chains. Decorin modulates collagen fibril formation as well as the bioactivity of various members of the transforming growth factor-beta (TGFbeta) superfamily. Decorin is initially translated as a preproprotein with an N-terminal signal peptide (aa1-16) and propeptide (aa17-30) sequence. Sequential removal of the signal peptide and the propeptide sequence produces pro- and mature decorin, respectively. (PMID 20026052).
      References
      Product Information
      FormatSerum
      PresentationRabbit polyclonal antibody serum with 0.05% sodium azide.
      Quality LevelMQ300
      Applications
      ApplicationAnti-Decorin Antibody is an antibody against Decorin for use in Immunohistochemistry, Western Blotting.
      Key Applications
      • Immunohistochemistry
      • Western Blotting
      Application NotesWestern Blotting Analysis: A 1:1,000 dilution from a representative lot detected Decorin in mouse knee joint extract.
      Biological Information
      ImmunogenCSA-conjugated linear peptide corresponding to the mature chain of mouse Decorin.
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      SpecificityReacts with decorin preproprotein, pro-decorin, as well as the mature decorin. This polyclonal antiserum is also known by LF-114.
      Species Reactivity
      • Mouse
      Species Reactivity NoteMouse. Predicted to react with Rat based on 100% sequence homology.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • Dcn
      Purification MethodUnpurified
      UniProt Number
      Molecular Weight39.7 kDa calculated
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Immunohistochemistry in mouse skin tissue.

      Immunohistochemistry Analysis: A 1:500 dilution of this antibody detected Decorin in mouse skin tissue.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Packaging Information
      Material Size200 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABT274 04055977169232