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OP93 Anti-BRCA1 (Ab-2) Mouse mAb (MS13)

Anti-BRCA1 (Ab-2), mouse monoclonal, clone MS13, recognizes ~220 kDa BRCA1 in MCF-7 cells. It is validated for Western blotting, immunofluorescence, immunoprecipitation, and for paraffin sections.

Anti-BRCA1 (Ab-2) Mouse mAb (MS13) MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Anti-Breast Cancer Susceptibility Protein

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OP93
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Overview

Key Spec Table

Species ReactivityHostAntibody Type
HMMonoclonal Antibody

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OP93-100UG
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      Description
      OverviewRecognizes the ~220 kDa BRCA1 protein in MCF-7 cells. Does not react with blood group antigens or growth factor receptors such as EGFR. Sold under license of U.S. Patent 5,753,441 and 6,162,897.
      Catalogue NumberOP93
      Brand Family Calbiochem®
      SynonymsAnti-Breast Cancer Susceptibility Protein
      References
      ReferencesScully, R., et al. 1996. Science 272, 123.
      Gudas, J.M., et al. 1996. Cell Growth Differ. 7, 717.
      Vaughn, J.P., et al. 1996. Cell Growth Differ. 7, 711.
      Goldgar, D.E. and Reilly, P.R. 1995. Nat. Genet. 11, 113.
      Merajver, S.D., et al. 1995. Clin. Can. Res. 1, 539.
      Merajver, S.D., et al. 1995. Nat. Genet. 9, 439.
      Struewing, J.P., et al. 1995. Nat. Genet. 11, 198.
      Thompson, M.E., et al. 1995. Nat. Genet. 9, 444.
      Futreal, P.A., et al. 1994. Science 266, 120.
      Miki, Y., et al. 1994. Science 266, 66.
      Product Information
      DeclarationSold under license of U.S. Patents 5,753,441 and 6,162,897.
      FormLiquid
      FormulationIn 0.05 M sodium phosphate buffer, 0.2% gelatin.
      Positive controlMCF7 cells
      Preservative≤0.1% sodium azide
      Quality LevelMQ100
      Applications
      Application ReferencesImmunoblotting, Immunoprecipitation, Immunofluorescence, Paraffin Sections Scully, R., et al. 1996. Science 272, 123.
      Key Applications Immunoblotting (Western Blotting)
      Immunofluorescence
      Immunoprecipitation
      Paraffin Sections
      Application NotesImmunoblotting (2 µg/ml, chemiluminescence; see application references)
      Immunofluorescence (see application references)
      Immunoprecipitation (see application references)
      Paraffin Sections (see application references)
      Application CommentsAntibody should be titrated for optimal results in individual systems.
      Biological Information
      Immunogenrecombinant, human BRCA1
      ImmunogenHuman
      Epitopewithin amino acids 1-304
      CloneMS13
      HostMouse
      IsotypeIgG₁
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Concentration Label Please refer to vial label for lot-specific concentration
      Storage and Shipping Information
      Ship Code Blue Ice Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Do not freeze Yes
      Global Trade Item Number
      Catalogue Number GTIN
      OP93-100UG 04055977209693