Aervent® Membrane in Optiseal® Filters
Optiseal filters with Aervent membrane are designed for sterilizing applications, removing particles and microorganisms from gases and solvents.
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Optiseal filters with Aervent membrane are designed for sterilizing applications, removing particles and microorganisms from gases and solvents. Less
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Overview
Description
Optiseal™ filters with Aervent™ membrane are 0.2 µm hydrophobic cartridges. They are designed for sterilizing applications, removing particles and microorganisms from gases and solvents. They are made with PTFE membrane and polypropylene components for broad application compatibility. Optiseal filters with Aervent membrane are designed to be used with Optiseal housings.
For traceability and easy identification, each Optiseal cartridge is labeled with its lot number, serial number, pore size and an abbreviated catalogue number.
Optiseal filters with Aervent membrane are designed, developed and manufactured in accordance with a Quality Management System approved by an accredited registered body to an ISO® 9000 Quality Systems Standard. Each unit is 100% integrity tested during manufacturing to guarantee integrity.
Typical Applications
Optiseal Aervent hydrophobic cartridges will remove particles and microorganisms from gases and liquids for low flow rates. In gases this filter will remove contamination down to 0.01 µm.
- Sterile tank venting
- Fermentation air applications
- Bioreactor inlet and outlet filtration
- Autoclaves
- Sterile process gases
Specifications
| Materials of Construction | |
| Filter Membrane | Polytetrafluoroethylene (PTFE) |
| Structural Components | Polypropylene |
| Filter Supports | Polypropylene |
| O-rings | Silicone (SI) |
| Pore Size | 0.2 µm |
| Filtration Area | 0.18 m² |
| Maximum Differential Pressure, bar (psid) | Forward: 5.5 bar (80 psid) @ 25 °C; 1.7 bar (25 psid) @ 80 °C; 0.35 bar (5 psid) @ 135 °C. Reverse: 4.1 bar (60 psid) |
| Bubble Point at 23 °C | ≥1100 mbar (16 psig) nitrogen with 70/30 % IPA/water |
| Nitrogen Diffusion at 23 °C | ≤6 mL/min @ 965 mbar (14 psig) in 70/30 % IPA/water |
| Bacterial Retention | Samples were quantitatively retentive of a minimum Brevundimonas diminuta challenge concentration of 1 x 10⁷ CFU/cm² using ASTM® F838 methodology. |
| Sterilization | 80 (40 forward/40 reverse) SIP cycles of 30 min @ 135 °C; 80 autoclave cycles of 30 min @ 135 °C |
| Good Manufacturing Practices | These products are manufactured in a facility which adheres to FDA Good Manufacturing Practices. |
| Non-Fiber Releasing | Component materials meet the "non-fiber releasing" criteria as defined in 21 CFR 210.3 (b) (6). |
| Component Material Toxicity | Component materials meet the criteria of the USP <88> Reactivity Test for Class VI Plastics. These products meet the requirements of the USP <88> Safety Test, utilizing a 0.9% sodium chloride extraction. |
| Certificate of Quality | Each cartridge is shipped with a Certificate of Quality which summarizes our stringent manufacturing and quality standards. |
Typical Air Flow Rate vs Pressure Drop at 25 °C
Ordering Information
Documentation
FAQ
| Question | Answer |
|---|---|
| Can I mount my tank vent filter horizontally? | Millipore recommends that you mount your vent filter vertically because it will facilitate the draining of any condensate that may collects in the bottom of the housing. If condensate builds up in the housing, it can cause part of the filter to becomes wet which will prevent air from passing through. |
Related Products & Applications
Product Families
Aervent® Hydrophobic Cartridge and Disposable Capsule FiltersSuperior filters for the sterile filtration of gases.Learn More >> |
Aervent® Membrane in Optiseal®-M FiltersOptiseal-M filters with Aervent membrane are designed for sterilizing applications, removing particles and microorganisms from gases and solvents.Learn More >> |
Optiseal Sanitary Cartridge Housings European VersionThe Optiseal housing is designed for sterile filtration of aqueous solutions and gases using Optiseal cartridge filters.Learn More >> |
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| Optiseal® |
Categories
| Biopharmaceutical Manufacturing > Downstream Processing > Sterile Filtration > Sterile Gas > Aervent |
| Materials of Construction | |
| Filter Membrane | Polytetrafluoroethylene (PTFE) |
| Structural Components | Polypropylene |
| Filter Supports | Polypropylene |
| O-rings | Silicone (SI) |
| Pore Size | 0.2 µm |
| Filtration Area | 0.18 m² |
| Maximum Differential Pressure, bar (psid) | Forward: 5.5 bar (80 psid) @ 25 °C; 1.7 bar (25 psid) @ 80 °C; 0.35 bar (5 psid) @ 135 °C. Reverse: 4.1 bar (60 psid) |
| Bubble Point at 23 °C | ≥1100 mbar (16 psig) nitrogen with 70/30 % IPA/water |
| Nitrogen Diffusion at 23 °C | ≤6 mL/min @ 965 mbar (14 psig) in 70/30 % IPA/water |
| Bacterial Retention | Samples were quantitatively retentive of a minimum Brevundimonas diminuta challenge concentration of 1 x 10⁷ CFU/cm² using ASTM® F838 methodology. |
| Sterilization | 80 (40 forward/40 reverse) SIP cycles of 30 min @ 135 °C; 80 autoclave cycles of 30 min @ 135 °C |
| Good Manufacturing Practices | These products are manufactured in a facility which adheres to FDA Good Manufacturing Practices. |
| Non-Fiber Releasing | Component materials meet the "non-fiber releasing" criteria as defined in 21 CFR 210.3 (b) (6). |
| Component Material Toxicity | Component materials meet the criteria of the USP <88> Reactivity Test for Class VI Plastics. These products meet the requirements of the USP <88> Safety Test, utilizing a 0.9% sodium chloride extraction. |
| Certificate of Quality | Each cartridge is shipped with a Certificate of Quality which summarizes our stringent manufacturing and quality standards. |
Typical Air Flow Rate vs Pressure Drop at 25 °C