Millipore Sigma Vibrant Logo

123040 AICA-Riboside - CAS 2627-69-2 - Calbiochem

AICA-Riboside, CAS 2627-69-2, is a cell-permeable nucleoside compound whose phosphorylated metabolite activates AMPK and acts as a regulator of de novo purine synthesis.

AICA-Riboside - CAS 2627-69-2 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Acadesine, AICAr, 5-Aminoimidazole-4-carboxamide-1-β-riboside, Z-Riboside, AMPK Signaling Activator II

Primary Target: Adenosine monophosphate-activated protein kinase (AMPK)
View Products on Sigmaaldrich.com
123040
View Pricing & Availability

Overview

Key Spec Table

CAS #Empirical Formula
2627-69-2C₉H₁₄N₄O₅

Pricing & Availability

Catalogue Number AvailabilityPackaging Qty/Pack Price Quantity
123040-50MG
—
Limited Availability Limited Availability
In Stock 
Discontinued
Limited Quantities Available
Availability to be confirmed
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

      		 Plastic ampoule 50 mg
      Price could not be retrieved
      Minimum Quantity is a multiple of
      Maximum Quantity is
      Upon Order Completion More Information
      You Saved ()
       
      —
      Request Pricing
      		 —
      Add To Favorites
      Description
      OverviewA cell-permeable nucleoside compound whose phosphorylated metabolite activates adenosine monophosphate-activated protein kinase (AMPK) and acts as a regulator of de novo purine synthesis. Stimulates glucose uptake in perfused and isolated muscle. Offers protection against cell death induced by glucose deprivation, chemical hypoxia, and exposure to glutamate and Aβ peptide.
      Catalogue Number123040
      Brand Family Calbiochem®
      SynonymsAcadesine, AICAr, 5-Aminoimidazole-4-carboxamide-1-β-riboside, Z-Riboside, AMPK Signaling Activator II
      References
      ReferencesMeli, M., et al. 2006. J. Med. Chem. in press.
      Culmsee, C., et al. 2001. J. Mol. Neurosci. 17, 45.
      Muoio, D.M., et al. 1999. Biochem. J. 338, 783.
      Hayashi, T., et al. 1998. Diabetes 47, 1369.
      Corton, J.M., et al. 1995. Eur. J. Biochem. 229, 558.
      Product Information
      CAS number2627-69-2
      ATP CompetitiveN
      FormWhite to brown solid
      Hill FormulaC₉H₁₄N₄O₅
      Chemical formulaC₉H₁₄N₄O₅
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Biological Information
      Primary TargetAdenosine monophosphate-activated protein kinase (AMPK)
      Purity≥98% by HPLC
      Physicochemical Information
      Cell permeableY
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Global Trade Item Number
      Catalogue Number GTIN
      123040-50MG 04055977206272