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104551 ACC2 Inhibitor, CD-017-0191 - Calbiochem

Overview

Key Spec Table

Empirical Formula
C₂₀H₁₉N₃O₃S

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104551-10MG
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      Glass bottle 10 mg
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      Description
      OverviewA cell-permeable and selective inhibitor of human Acetyl-CoA carboxylase 2 (ACC2) (IC50 = 2.8 µM), which does not inhibit human ACC1 at all at concentrations up to 100 µM, in vitro. It is also shown to inhibit the growth of yeast (IC50 = 3.8 µM), in which the native ACC1 gene is replaced with the human ACC2 strain; but not with the human ACC1 strain at concentrations ≤ 100 µM. This compound is not demonstrated to be toxic to human cells in culture at concentrations up to 10 µM.
      Catalogue Number104551
      Brand Family Calbiochem®
      Synonyms2-((2-(4-isopropoxyphenyl)-5-methyloxazol-4-yl)methylthio)oxazolo[4,5-b]pyridine
      References
      ReferencesMarjanovic, J., et al. 2010 Proc. Natl. Acad. Sci. 107, 9093.
      Product Information
      FormOff-white solid
      Hill FormulaC₂₀H₁₉N₃O₃S
      Chemical formulaC₂₀H₁₉N₃O₃S
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Biological Information
      Purity≥90% by HPLC
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Global Trade Item Number
      Catalogue Number GTIN
      104551-10MG 04055977226478