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343922 5-Fluorouracil - CAS 51-21-8 - Calbiochem

Potent antitumor agent.

5-Fluorouracil - CAS 51-21-8 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 5-FU

Primary Target: Aminoisobutyrate-pyruvate aminotransferase
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343922
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
51-21-8C₄H₃FN₂O₂

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      Description
      OverviewPotent antitumor agent. Inhibits aminoisobutyrate-pyruvate aminotransferase. Induces apoptosis in human colon cancer cell lines.
      Catalogue Number343922
      Brand Family Calbiochem®
      Synonyms5-FU
      References
      ReferencesPressacco, J., et al. 1996. Br. J. Cancer 72, 939.
      Shchepotin, I.B., et al. 1994. Anticancer Res. 14, 1027.
      Product Information
      CAS number51-21-8
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₄H₃FN₂O₂
      Chemical formulaC₄H₃FN₂O₂
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetAminoisobutyrate-pyruvate aminotransferase
      Purity≥98% by HPLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSYR0350000
      Safety Information
      R PhraseR: 21/22

      Harmful in contact with skin and if swallowed.
      S PhraseS: 36/37

      Wear suitable protective clothing and gloves.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Harmful
      Storage +2°C to +8°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      343922-1GM 04055977195132

      Documentation

      5-Fluorouracil - CAS 51-21-8 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      5-Fluorouracil - CAS 51-21-8 - Calbiochem Certificates of Analysis

      TitleLot Number
      343922

      References

      Reference overview
      Pressacco, J., et al. 1996. Br. J. Cancer 72, 939.
      Shchepotin, I.B., et al. 1994. Anticancer Res. 14, 1027.

      Brochure

      Title
      Tools and Tips for Analyzing Apoptosis
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision02-May-2008 RFH
      Synonyms5-FU
      DescriptionPotent antitumor agent that inhibits aminoisobutyrate-pyruvate aminotransferase. Induces apoptosis of human colon cancer cell lines.
      FormWhite solid
      CAS number51-21-8
      RTECSYR0350000
      Chemical formulaC₄H₃FN₂O₂
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityDMF (5 mg/ml), DMSO (5 mg/ml), Methanol (1 mg/ml), or hot H₂O (1 mg/ml)
      Storage +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Harmful
      Merck USA index14, 4181
      ReferencesPressacco, J., et al. 1996. Br. J. Cancer 72, 939.
      Shchepotin, I.B., et al. 1994. Anticancer Res. 14, 1027.