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538927 15d-PGJ₂ - CAS 87893-55-8 - Calbiochem

A metabolite of PGD₂that has recently been identified as a natural ligand for PPARγ-dependent adipogenesis in transfected NIH/3T3 cells and for PPARγ response element (PPRE) in CV-1 cells.

15d-PGJ₂ - CAS 87893-55-8 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Prostaglandin J₂, 15-Deoxy-Δ12,14, PPAR Agonist VII, PPARγ Agonist VI

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538927
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
87893-55-8C₂₀H₂₈O₃

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538927-1MG
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      Description
      OverviewA metabolite of PGD2 that has recently been identified as a natural ligand for PPARγ-dependent adipogenesis in transfected NIH/3T3 cells and for PPARγ response element (PPRE) in CV-1 cells. Competes with thiazolidinediones for PPARγ binding. Down-regulates inducible nitric oxide synthase (iNOS).
      Catalogue Number538927
      Brand Family Calbiochem®
      SynonymsProstaglandin J₂, 15-Deoxy-Δ12,14, PPAR Agonist VII, PPARγ Agonist VI
      References
      ReferencesPetrova, T.V., et al. 1999. Proc. Natl. Acad. Sci. USA 96, 4668.
      Ricote, M., et al. 1998. Nature 391, 79.
      Forman, B.M., et al. 1995. Cell 83, 803.
      Kliewer, S.A., et al. 1995. Cell 83, 813.
      Product Information
      CAS number87893-55-8
      ATP CompetitiveN
      FormOil
      Hill FormulaC₂₀H₂₈O₃
      Chemical formulaC₂₀H₂₈O₃
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetA natural ligand for PPARγ-dependent adipogenesis
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 20/21/22

      Harmful by inhalation, in contact with skin and if swallowed.
      S PhraseS: 36

      Wear suitable protective clothing.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Blue Ice Only
      Toxicity Harmful
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      538927-1MG 04055977195279

      Documentation

      15d-PGJ₂ - CAS 87893-55-8 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      15d-PGJ₂ - CAS 87893-55-8 - Calbiochem Certificates of Analysis

      TitleLot Number
      538927

      References

      Reference overview
      Petrova, T.V., et al. 1999. Proc. Natl. Acad. Sci. USA 96, 4668.
      Ricote, M., et al. 1998. Nature 391, 79.
      Forman, B.M., et al. 1995. Cell 83, 803.
      Kliewer, S.A., et al. 1995. Cell 83, 813.

      Brochure

      Title
      Bioactive Lipids Technical Bulletin
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision15-July-2016 JSW
      SynonymsProstaglandin J₂, 15-Deoxy-Δ12,14, PPAR Agonist VII, PPARγ Agonist VI
      DescriptionA metabolite of PGD2 that has recently been identified as a natural ligand for PPARγ-dependent adipogenesis in transfected 3T3 cells and for PPARγ response element (PPRE) in CV-1 cells. Competes with thiazolidinediones for PPARγ binding.
      FormOil
      Intert gas (Yes/No) Packaged under inert gas
      CAS number87893-55-8
      Chemical formulaC₂₀H₂₈O₃
      Structure formulaStructure formula
      Purity≥95% by HPLC
      SolubilityDMSO (25 mg/ml) or ethanol (25 mg/ml)
      Storage -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Harmful
      ReferencesPetrova, T.V., et al. 1999. Proc. Natl. Acad. Sci. USA 96, 4668.
      Ricote, M., et al. 1998. Nature 391, 79.
      Forman, B.M., et al. 1995. Cell 83, 803.
      Kliewer, S.A., et al. 1995. Cell 83, 813.