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260575 1-Deoxymannojirimycin, Hydrochloride - CAS 84444-90-6 - Calbiochem

A specific α-mannosidase I inhibitor that blocks conversion of high mannose to complex oligosaccharides.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: DMJ, 1,5-Dideoxy-1,5-imino-D-mannitol, HCl

Primary Target: α-mannosidase-I
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      Overview

      Replacement Information

      Key Spec Table

      CAS #Empirical Formula
      84444-90-6C₆H₁₃NO₄·HCl
      Description
      OverviewA specific α-mannosidase I inhibitor that blocks conversion of high mannose to complex oligosaccharides.
      Catalogue Number260575
      Brand Family Calbiochem®
      SynonymsDMJ, 1,5-Dideoxy-1,5-imino-D-mannitol, HCl
      References
      ReferencesSuzuki, S.S., and Piette, L.H. 1993. J. Cell. Biochem. 51, 181.
      Fuhrmann, U., et al. 1984. Nature 307, 755.
      Product Information
      CAS number84444-90-6
      ATP CompetitiveN
      FormWhite crystalline solid
      Hill FormulaC₆H₁₃NO₄·HCl
      Chemical formulaC₆H₁₃NO₄·HCl
      Hygroscopic Hygroscopic
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Targetα-mannosidase-I
      Purity≥98% by TLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 20/21/22

      Harmful by inhalation, in contact with skin and if swallowed.
      S PhraseS: 36

      Wear suitable protective clothing.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Harmful
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 6 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      260575 0

      Documentation

      1-Deoxymannojirimycin, Hydrochloride - CAS 84444-90-6 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      1-Deoxymannojirimycin, Hydrochloride - CAS 84444-90-6 - Calbiochem Certificates of Analysis

      TitleLot Number
      260575

      References

      Reference overview
      Suzuki, S.S., and Piette, L.H. 1993. J. Cell. Biochem. 51, 181.
      Fuhrmann, U., et al. 1984. Nature 307, 755.

      Citations

      Title
    • William D. Hanley, et al. (2005) CD44 on LS174T Colon Carcinoma Cells Possesses E-Selectin Ligand Activity. Cancer Research 65, 5812-5817.
    • Jenny J.L. Ho, et al. (2003) N-glycosylation is required for the surface localization of MUC17 mucin. 23, 585-592.
      		•
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision28-April-2008 JSW
      SynonymsDMJ, 1,5-Dideoxy-1,5-imino-D-mannitol, HCl
      DescriptionSpecial α-mannosidase I inhibitor that blocks conversion of high mannose to complex oligosaccharides.
      FormWhite crystalline solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number84444-90-6
      Chemical formulaC₆H₁₃NO₄·HCl
      Structure formulaStructure formula
      Purity≥98% by TLC
      SolubilityEthanol (1 mg/ml) or H₂O (1 mg/ml)
      Storage -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 6 months at -20°C.
      Toxicity Harmful
      ReferencesSuzuki, S.S., and Piette, L.H. 1993. J. Cell. Biochem. 51, 181.
      Fuhrmann, U., et al. 1984. Nature 307, 755.
      Citation
    • William D. Hanley, et al. (2005) CD44 on LS174T Colon Carcinoma Cells Possesses E-Selectin Ligand Activity. Cancer Research 65, 5812-5817.
    • Jenny J.L. Ho, et al. (2003) N-glycosylation is required for the surface localization of MUC17 mucin. 23, 585-592.
      		•