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673000 Vacuolin-1 - CAS 351986-85-1 - Calbiochem

A cell-permeable triazine based compound that inhibits Ca2+-dependent fusion of lysosomes with the plasma membrane and the release of lysosomal content, without affecting enlargeosomes or other membra

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Vacuolin-1 - CAS 351986-85-1 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Primary Target: Ca2+-dependent fusion of lysosomes with the plasma membrane
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673000
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Overview

Key Spec Table

CAS #Empirical Formula
351986-85-1C₂₆H₂₄IN₇O

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673000-10MG
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      Description
      OverviewA cell-permeable triazine based compound that inhibits Ca2+-dependent fusion of lysosomes with the plasma membrane and the release of lysosomal content, without affecting enlargeosomes or other membrane-bound organelles. It does not disturb the organization of the actin or tubulin cytoskeletal network, nor does it interfere with membrane traffic along the constitutive pathway from the ER to the plasma membrane.
      Catalogue Number673000
      Brand Family Calbiochem®
      References
      ReferencesCerny, J., et al. 2004. EMBO Rep. 5, 883.
      Product Information
      CAS number351986-85-1
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₂₆H₂₄IN₇O
      Chemical formulaC₂₆H₂₄IN₇O
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Biological Information
      Primary TargetCa2+-dependent fusion of lysosomes with the plasma membrane
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableY
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Global Trade Item Number
      Catalogue Number GTIN
      673000-10MG 04055977183511